Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Patients with mild gallstone pancreatitis can undergo surgery sooner, shortening hospital stays

05.02.2010
LA BioMed study finds operations can be safely performed within 48 hours of admission

Patients with mild gallstone pancreatitis usually stay in the hospital for several days, waiting for the symptoms to subside, before undergoing surgery to remedy the condition. A new study from researchers at Los Angeles Biomedical Research Institute (LA BioMed) indicates patients may no longer have to wait so long for surgery and could leave the hospital sooner.

The study, slated for publication in the Annals of Surgery in April, found surgeons could safely operate on patients with mild gallstone pancreatitis within 48 hours of admission, rather than waiting for the painful inflammation in the pancreas to subside before performing the surgery.

"In the study, patients with mild pancreatitis, who underwent surgery within two days of admission, left the hospital sooner and had similar favorable outcomes as those patients who waited several days before surgery," said Christian de Virgilio, MD, a LA BioMed principal investigator and the corresponding author for the study. "The common practice of delaying surgery on patients with mild gallstone pancreatitis should be abandoned because it results in longer and more costly hospital stays."

Mild gallstone pancreatitis is caused by a gallstone or gallstones in the common bile duct triggering a backup in the pancreas of the digestive enzymes and hormones it produces to help the body digest food and convert glucose to energy.

The standard treatment is laparoscopic surgery to remove the gall bladder, which produces the gallstones. In the study reported in the Annals of Surgery, surgeons removed the gall bladders of 25 patients with mild gallstone pancreatitis within 48 hours of admission and operated on 24 other patients after lab tests and physical examinations found their enzyme levels had normalized. (One patient was excluded from the study after developing other unrelated medical complications.)

The researchers found operating on the patients within 48 hours of admission decreased the overall length of hospital stays from four to three days when compared with the patients who waited for the symptoms to subside before undergoing surgery.

"Operating within 48 hours of admission is ideally suited to patients with mild gallstone pancreatitis who don't demonstrate evidence of cholangitis, a bacterial infection, and don't require aggressive fluid resuscitation," said Dr. de Virgilio.

The researchers conducted the study at Harbor-UCLA Medical Center, a Los Angeles County teaching hospital, from November 2007 to November 2008. The study is available for purchase in pre-print format online at http://journals.lww.com/annalsofsurgery/toc/publishahead.

About LA BioMed

Founded in 1952, LA BioMed is one of the country's largest nonprofit independent biomedical research institutes. It conducts biomedical research, educates young scientists and provides community services, including childhood immunization and nutrition assistance. The institute's researchers conduct studies in such areas as cardiovascular disease, emerging infections, cancer, diabetes, kidney disease, dermatology, reproductive health, respiratory disorders and inherited illnesses. LA BioMed is academically affiliated with the David Geffen School of Medicine at UCLA and located on the Harbor-UCLA Medical Center campus.

Laura Mecoy | EurekAlert!
Further information:
http://www.LABioMed.org

More articles from Studies and Analyses:

nachricht Amputees can learn to control a robotic arm with their minds
28.11.2017 | University of Chicago Medical Center

nachricht The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>