For the study, published this week in the Early Edition of the Proceedings of the National Academy of Sciences, researchers showed individuals with memory loss clips of happy and sad movies. Although the participants couldn't recall what they had watched, they retained the emotions elicited by the clips.
Justin Feinstein, lead study author and a UI doctoral student in clinical neuropsychology, says the discovery has direct implications for Alzheimer's disease.
"A simple visit or phone call from family members might have a lingering positive influence on a patient's happiness even though the patient may quickly forget the visit or phone call," Feinstein said. "On the other hand, routine neglect from staff at nursing homes may leave the patient feeling sad, frustrated and lonely even though the patient can't remember why."
Feinstein conducted the study with UI neuroscience faculty members Daniel Tranel, Ph.D., UI professor of neurology and psychology, and Melissa Duff, Ph.D., UI assistant professor of communication sciences and disorders.
The researchers studied five rare neurological patients with damage to their hippocampus, a part of the brain that's critical for transferring short-term memories into long-term storage. Damage to the hippocampus prevents new memories from being acquired.
This same type of amnesia is an early sign of Alzheimer's disease.
The experiment started with an emotion-induction technique using powerful film clips. Each amnesic patient viewed 20 minutes of either sad or happy movies on separate days. The movies triggered the appropriate emotion, ranging from intense bouts of laughter during happy films to tears of sorrow during sad ones.
About 10 minutes after the clip ended, researchers gave patients a memory test to see if they could recall what they had watched. As expected, the patients were extremely impaired. A healthy person recalls about 30 details from each clip, but one patient couldn't recall a single detail.
After the memory test, patients answered questions to gauge their emotions.
"Indeed, they still felt the emotion. Sadness tended to last a bit longer than happiness, but both emotions lasted well beyond their memory of the films," Feinstein said. "With healthy people, you see feelings decay as time goes on. In two patients, the feelings didn't decay; in fact, their sadness lingered."
These findings challenge the popular notion that erasing a painful memory can abolish psychological suffering. They also reinforce the importance of attending to the emotional needs of people with Alzheimer's, which is expected to affect as many as 100 million people worldwide by 2050.
"Age is the greatest risk factor for Alzheimer's, and there's currently no cure," Feinstein said. "What we're about to face is an epidemic. We're going to have more and more baby boomers getting older, and more and more people with Alzheimer's disease. The burden of care for these individuals is enormous.
"What this research suggests is that we need to start setting a scientifically informed standard of care for patients with memory disorders. Here is clear evidence showing that the reasons for treating Alzheimer's patients with respect and dignity go beyond simple human morals."
The study was funded by the Fraternal Order of Eagles, the National Institutes of Health, the National Science Foundation and the Kiwanis International Foundation.
STORY SOURCE: University of Iowa Graduate College Office of External Relations, 205 Gilmore Hall, Iowa City, Iowa 52242-2500
John Riehl | Newswise Science News
WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf
First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...
A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.
Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
18.05.2018 | Power and Electrical Engineering
18.05.2018 | Information Technology
18.05.2018 | Information Technology