Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Nordic study shows marginally higher but overall low risk of stillbirth in ART children

06.07.2011
The group looked at 60,650 singletons in a common Nordic database from ART registers in Denmark, Finland, Norway and Sweden and compared these to a control group of 360,022 naturally conceived (NC) singletons.

In both groups 0.4 % of singletons were stillborn, with a definition of stillbirth as a dead child after 22 weeks of gestation. After having been matched with the control group regarding mother's parity and year of birth, the overall risk of stillbirth was found to be marginally higher (1.1 fold) in ART children after adjusting for factors such as maternal age and the child's sex.

"Although the difference in risk of stillbirth is significant between the two groups and the risk is marginally higher with an overrepresentation of 8 per 1,000 pregnancies for singleton ART pregnancies, the overall risk of stillbirth is still low," said Anna-Karina Aaris Henningsen, leading author of the study from Righospitalet University Hospital of Copenhagen. "This means that the individual woman need not be concerned about the risk of stillbirth during pregnancy."

When analysing the stillbirth risk before and after term, no difference was found after 40 weeks of gestation between ART children and their naturally conceived peers. This was also the case when comparing the two cohorts after 37 weeks of gestation. However, until gestational week 40, the group found a 1.2 fold higher risk of stillbirth for ART singletons.

... more about:
»Aaris »Nordic »perinatal death

"We believe the difference in risk of stillbirth between ART and NC children seems to occur before 37 weeks of gestation," said Dr. Aaris Henningsen. "It is likely, that some of the difference in risk of stillbirth is related to parental factors in the subfertile mother or father."

When the researchers assessed the risk of total perinatal death (risk of stillbirth and risk of perinatal death until one year of age), children born after ART showed a 1.4 fold increased risk compared to naturally conceived babies. This remained 1.2 fold higher after adjusting for confounding factors and can probably be partly explained by the higher risk of preterm birth among ART children.

"Very few European, non-Nordic, studies exist on stillbirth rates and are mostly based on small numbers," explained Dr. Aaris Henningsen. "Our results come from the largest database on ART children worldwide. The MART group is currently looking at multiple neonatal outcomes including the risk of perinatal death in both singletons and twins and is hoping to have additional data in the near future."

Background

In 2006, the European IVF Monitoring Group (EIM), a working group of ESHRE decided to assess the possibility of using the Nordic ART registers to pool outcome data for infant and maternal health after ART. The Committee on Nordic ART and Safety (CoNARTaS) was established in order to provide a continuous and large scale Nordic monitoring system that reports on safety and quality aspects of ART. The Nordic ART database contains data on all ART pregnancies, deliveries and children born after IVF, Intracytoplasmic Sperm Injection (ICSI) and frozen embryo transfer (FET) in Denmark, Finland, Norway and Sweden.

Abstract no: O-300 Wednesday 6 July 2011, 14.30 hrs CEST (Room K1+K2)

Note: When obtaining outside comment, journalists are requested to ensure that their contacts are aware of the embargo on this release.

The figures in the release have been updated since the abstract was submitted to the conference.

For further information on the details contained in this press release, contact:
In English, German, Spanish, French
Hanna Hanssen
Tel: + 32 (0)2 263 64 66
Mobile: + 32 (0) 473 35 33 81
Email: hanna@eshre.eu

Hanna Hanssen | EurekAlert!
Further information:
http://www.eshre.eu

Further reports about: Aaris Nordic perinatal death

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Transport of molecular motors into cilia

28.03.2017 | Life Sciences

A novel hybrid UAV that may change the way people operate drones

28.03.2017 | Information Technology

NASA spacecraft investigate clues in radiation belts

28.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>