A study suggests that a new treatment called repetitive transcranial magnetic stimulation (rTMS) may lessen the non-pain symptoms of fibromyalgia, such as emotional and social disorders, and improve quality of life. The research is published in the March 26, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Fibromyalgia is a disease known for the main symptom of pain, however, it may also cause tiredness, interrupted sleep, depression, dizziness, digestive problems, headache, tingling, numbness and frequent urination.
“About five million Americans experience fibromyalgia, which affects women more often than men,” said study author Eric Guedj, MD, PhD, with Aix-Marseille University and National Center for Scientific Research in Marseille, France. “rTMS is a way to alter the excitability of the brain targeted by the device. A treatment such as this may provide a safe and noninvasive complement to pain pills in some people.”
For the study, 38 people who had persistent fibromyalgia pain for more than six months were randomly assigned to receive either rTMS or sham stimulation for 14 sessions over 10 weeks. For the sham stimulation, the electromagnetic coil looked and sounded like the actual treatment, but no stimulation was given. The researchers then assessed the changes in quality of life at the eleventh week, measured by a questionnaire, as well as brain metabolic changes using PET neuroimaging.
The study found that at week 11, people who received the rTMS therapy had greater improvement in quality of life and in mental components of the questionnaire than those in the sham stimulation group.
The improvement in quality of life involved mainly affective (mood or feelings), emotional (joy, sadness, anger, anxiety), and social areas (work performance, participation in social activities, contact with friends and engaging in hobbies and interests), and was correlated with brain PET metabolic changes.
At the beginning of the study, those receiving the treatment had an average score of 60 on the quality of life questionnaire, where scores range from zero to 100 and lower scores indicate better quality of life. Those receiving the sham treatment had an average score of 64.
After 11 weeks, the average score of those receiving the treatment had dropped by about 10 points, while the average score had increased by two points for those receiving the sham treatment.
The study was supported by Marseille Public Hospitals (APHM) and the French National Institute of Health and Medical Research (INSERM).
To learn more about fibromyalgia, please visit www.aan.com/patients.
The American Academy of Neurology, an association of more than 27,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.
Rachel L. Seroka | American Academy of Neurology
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy