A study suggests that a new treatment called repetitive transcranial magnetic stimulation (rTMS) may lessen the non-pain symptoms of fibromyalgia, such as emotional and social disorders, and improve quality of life. The research is published in the March 26, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Fibromyalgia is a disease known for the main symptom of pain, however, it may also cause tiredness, interrupted sleep, depression, dizziness, digestive problems, headache, tingling, numbness and frequent urination.
“About five million Americans experience fibromyalgia, which affects women more often than men,” said study author Eric Guedj, MD, PhD, with Aix-Marseille University and National Center for Scientific Research in Marseille, France. “rTMS is a way to alter the excitability of the brain targeted by the device. A treatment such as this may provide a safe and noninvasive complement to pain pills in some people.”
For the study, 38 people who had persistent fibromyalgia pain for more than six months were randomly assigned to receive either rTMS or sham stimulation for 14 sessions over 10 weeks. For the sham stimulation, the electromagnetic coil looked and sounded like the actual treatment, but no stimulation was given. The researchers then assessed the changes in quality of life at the eleventh week, measured by a questionnaire, as well as brain metabolic changes using PET neuroimaging.
The study found that at week 11, people who received the rTMS therapy had greater improvement in quality of life and in mental components of the questionnaire than those in the sham stimulation group.
The improvement in quality of life involved mainly affective (mood or feelings), emotional (joy, sadness, anger, anxiety), and social areas (work performance, participation in social activities, contact with friends and engaging in hobbies and interests), and was correlated with brain PET metabolic changes.
At the beginning of the study, those receiving the treatment had an average score of 60 on the quality of life questionnaire, where scores range from zero to 100 and lower scores indicate better quality of life. Those receiving the sham treatment had an average score of 64.
After 11 weeks, the average score of those receiving the treatment had dropped by about 10 points, while the average score had increased by two points for those receiving the sham treatment.
The study was supported by Marseille Public Hospitals (APHM) and the French National Institute of Health and Medical Research (INSERM).
To learn more about fibromyalgia, please visit www.aan.com/patients.
The American Academy of Neurology, an association of more than 27,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.
Rachel L. Seroka | American Academy of Neurology
Climate study finds evidence of global shift in the 1980s
26.11.2015 | Leibniz-Institut für Gewässerökologie und Binnenfischerei (IGB)
Network analysis shows systemic risk in mineral markets
16.11.2015 | International Institute for Applied Systems Analysis (IIASA)
Chemical weathering of rocks over geological time scales is an important control on the stability of the climate. This weathering is, in turn, highly dependent...
Before the fluid of the middle ear drains and sound waves penetrate for the first time, the inner ear cells of newborn rodents practice for their big debut. Researchers at Johns Hopkins report they have figured out the molecular chain of events that enables the cells to make “sounds” on their own, essentially “practicing” their ability to process sounds in the world around them.
The researchers, who describe their experiments in the Dec. 3 edition of the journal Cell, show how hair cells in the inner ear can be activated in the absence...
Planet Earth experienced a global climate shift in the late 1980s on an unprecedented scale, fuelled by anthropogenic warming and a volcanic eruption, according to new research published this week.
Scientists say that a major step change, or ‘regime shift’, in the Earth’s biophysical systems, from the upper atmosphere to the depths of the ocean and from...
The Fraunhofer Institute for Solar Energy Systems ISE has installed 70 photovoltaic modules on the outer façade of one of its lab buildings. The modules were...
Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.
In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid...
30.11.2015 | Event News
25.11.2015 | Event News
17.11.2015 | Event News
01.12.2015 | Social Sciences
01.12.2015 | Earth Sciences
30.11.2015 | Trade Fair News