Natural product combinations as potent as man-made drugs
Published in PLOS ONE in November 2012, the research showed that active ingredients in combinations of natural products can achieve the same level of potency as synthetic anticancer and antibacterial drugs but they have to be taken in larger quantities or for a longer period of time. These combinations include traditional Chinese medicine such as the Realgar-Indigo naturalis formula designed for the treatment of leukaemia, Wedelia chinensis for anti-inflammatory purposes and black tea used in Japan for the treatment of gastroenteritis.
Through an analysis of more than 1,601 previous studies conducted on natural products and 190 man-made drugs, the researchers found that natural products are generally 10 to 100 times weaker than man-made drugs. They concluded that combinations of natural products can achieve the same strength as man-made drugs, but with current traditional practices, the odds are low.
Prof Chen said, “There have been claims that natural products simply have a placebo effect. In our study, we looked at more than 100 types of natural product combinations that are perceived to be the best and found that it is possible for natural products to achieve the same effectiveness as man-made drugs. However, the probability of finding such combinations based on traditional methods is low (below 3 per cent) as the natural products have to be of sufficient potency and taken in the right combination.”
Next steps for research on natural products
The findings from this research provide a foundation for further studies on the clinical effectiveness of herbal medicine and how a combination of natural products and synthetic drugs can be taken together to fight diseases.
The team will continue to conduct more research in this area, in particular, to determine how to achieve the same level of effectiveness for natural products as synthetic drugs. Their research will focus on popular herbal products and frequently prescribed traditional medicine.
Kimberley Wang | Newswise
The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...
Scientists from the MPI for Chemical Energy Conversion report in the first issue of the new journal JOULE.
Cell Press has just released the first issue of Joule, a new journal dedicated to sustainable energy research. In this issue James Birrell, Olaf Rüdiger,...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
19.09.2017 | Event News
19.09.2017 | Physics and Astronomy
19.09.2017 | Power and Electrical Engineering