“We are looking for patterns of cancer development in animals, so we can find common risk factors,” said Kim Selting, associate teaching professor of oncology at the MU College of Veterinary Medicine. “I mentored a former resident, Kerry Rissetto, as she examined intestinal tumors in cats on a very large scale, and we believe we can use this information to eventually identify cancer risk factors and treatments for humans.”
Using a database, the researchers examined 1,129 cases covering 47 years of intestinal cancer in cats. The researchers found that most feline intestinal cancers were lymphoma, or cancer of the immune system, and most cancers were found in the small intestines. The researchers also determined that the Siamese breed, particularly males seven years old or older, had an increased risk of developing intestinal cancer.
“This is important because there are very few population-based studies that allow us to evaluate cancer and risk factors on such a large scale,” Selting said. “Pet owners should be on the lookout for unexplained weight loss, vomiting and diarrhea, because these issues can be associated with intestinal cancer.”
Selting says that tracking animal cancer is important because animals share the environment with humans. By noting patterns of cancer development, doctors and veterinarians may become aware of environmental factors that could be causing tumor progression in different species, including humans.
“Animal health care may predict what could be coming for human health care,” Selting said. “For example, dogs are really the only species, other than humans, that develop the toughest type of prostate cancers. If a treatment develops that can help with prostate cancer, we can test it on dogs and find results faster because cancer in dogs progresses faster than cancer in humans.”
The study “Recent Trends in Feline Intestinal Neoplasia: An Epidemiologic Study of 1,129 Cases in the Veterinary Medical Database from 1964 to 2004,” won an award for the best research generated from the Veterinary Medical Database (VMDB). The study was published in the Journal of the American Animal Hospital Association. In addition to Rissetto, other coauthors include J. Armando Villamil, Jeff Tyler, and Carolyn Henry, all from the University of Missouri.
The VMDB holds abstracts detailing 7 million discharged animal species from a consortium of veterinary teaching hospitals. MU was the second veterinary school to contribute data to the VMDB in the 1960s. While initially funded by the National Cancer Institute of the National Institutes of Health, the VMDB is now a not-for-profit corporation whose goal is to acquire, maintain and research clinical data sent from member teaching hospitals in the U.S. and Canada. Additional information on VMDB may be found at their website: http://www.vmdb.org.
The research reported in the published paper is part of Mizzou Advantage, the five unique areas that set MU apart from other universities. The project contributes to the “One Health/One Medicine: The Convergence of Human and Animal Health,” which expands on MU’s pioneering work in the convergence of human and animal health and connects it with research and instruction in health care delivery, health policy, medical ethics, health care business models and the culture of healthy living.
Steven Adams | EurekAlert!
Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)
The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
23.10.2017 | Event News
17.10.2017 | Event News
10.10.2017 | Event News
23.10.2017 | Physics and Astronomy
23.10.2017 | Earth Sciences
23.10.2017 | Health and Medicine