"Due to this association, there was also a link between farming or country living and developing Parkinson's in some of the studies," said study author Emanuele Cereda, MD, PhD, with the IRCCS University Hospital San Matteo Foundation in Pavia, Italy. The research was also conducted by Gianni Pezzoli, MD, with the Parkinson Institute – ICP, Milan.
For the analysis, researchers reviewed 104 studies that looked at exposure to weed, fungus, rodent or bug killers, and solvents and the risk of developing Parkinson's disease. Studies that evaluated the proximity of exposure, such as country living, work occupation and well water drinking were also included.
The research found that exposure to bug or weed killers and solvents increased the risk of developing Parkinson's disease by 33 to 80 percent. In controlled studies, exposure to the weed killer paraquat or the fungicides maneb and mancozeb was associated with two times the risk of developing the disease.
"We didn't study whether the type of exposure, such as whether the compound was inhaled or absorbed through the skin and the method of application, such as spraying or mixing, affected Parkinson's risk," said Cereda. "However, our study suggests that the risk increases in a dose response manner as the length of exposure to these chemicals increases."
The study was supported by the Grigioni Foundation for Parkinson's Disease and the IRCCS University Hospital San Matteo Foundation.To learn more about Parkinson's disease, please visit
Rachel Seroka | American Academy of Neurology
Do microplastics harbour additional risks by colonization with harmful bacteria?
05.04.2018 | Leibniz-Institut für Ostseeforschung Warnemünde
Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
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Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
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Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
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20.04.2018 | Physics and Astronomy