For the study, researchers reviewed the cases of 40 people from the Neurological Tissue Bank-University of Barcelona-Hospital Clínic-IDIBAPS in Barcelona, Spain, whose brains showed that they had Alzheimer’s disease in an autopsy. Researchers also reviewed information about the age at which the symptoms began and family history.
About 38 percent experienced initial symptoms other than memory problems.
The study found that one-third of people with confirmed early onset Alzheimer’s disease showed symptoms other than memory problems, such as behavior, vision or language problems and a decline in executive function, or the ability to carry out tasks. In people with atypical symptoms and no memory problems, 53 percent were incorrectly diagnosed when first seen by a doctor, compared to four percent of those who had memory problems. They were mainly diagnosed with other types of dementia. Of those with unusual initial symptoms, 47 percent were still incorrectly diagnosed at the time of their death.
“People who develop early onset Alzheimer’s disease often experience these atypical symptoms rather than memory problems, which can make getting an accurate diagnosis difficult,” said study author Albert Lladó, MD, PhD, with the Alzheimer’s Disease and Other Cognitive Disorders Unit, Hospital Clínic of Barcelona and the Institute of Biomedical Investigation August Pi i Sunyer (IDIBAPS), in Barcelona, Spain. “Biomarkers of Alzheimer’s disease and other disorders are needed for us to better recognize, diagnose and treat early onset Alzheimer’s disease sooner to improve the quality of life of these patients.”
The study was supported by a grant from the Hospital Clínic-Emili Letang.
The American Academy of Neurology, an association of more than 24,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.
For more information about the American Academy of Neurology, visit http://www.aan.com.VIDEO: http://www.youtube.com/AANChannel
Rachel L. Seroka | American Academy of Neurology
A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg
Urbanization to convert 300,000 km2 of prime croplands
27.12.2016 | Mercator Research Institute on Global Commons and Climate Change (MCC) gGmbH
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
18.01.2017 | Materials Sciences
18.01.2017 | Information Technology
18.01.2017 | Ecology, The Environment and Conservation