In a first-of-its-kind look at the efficacy of non-pharmaceutical interventions in controlling the spread of the flu virus in a community setting, researchers at the University of Michigan School of Public Health studied more than 1,000 student subjects from seven U-M residence halls during last year's flu season.
"The first-year results (2006-2007) indicate that mask use and alcohol-based hand sanitizer help reduce influenza- like illness rates, ranging from 10 to 50 percent over the study period," said Allison Aiello, co-principal investigator and assistant professor of epidemiology at the U-M SPH. Dr. Arnold Monto, professor of epidemiology, is also a principal investigator of the study.
Aiello stressed the first year of the two-year project, called M-Flu, was a very mild flu season and only a few cases were positive for flu, so results should be interpreted cautiously. Ongoing studies will test for other viruses that may be responsible for the influenza-like illness symptoms observed, she said.
"Nevertheless, these initial results are encouraging since masks and hand hygiene may be effective for preventing a range of respiratory illnesses," Aiello said.
The findings, "Mask Use Reduces Seasonal Influenza-like Illness In The Community Setting," was presented Sunday at The Interscience Conference on Antimicrobial Agents and Chemotherapy and the Infectious Diseases Society of America annual meeting in Washington, D.C.
At the start of flu season in the last two years, participants were randomly assigned to six weeks of wearing a standard medical procedure mask alone, mask use and hand sanitizer use, or a control group with no intervention. Researchers followed students for incidence of influenza like illness symptoms, defined as cough with at least one other characteristic symptom such as fever, chills or body aches, Monto said.
From the third week on, both the mask only and mask/hand sanitizer interventions showed a significant or nearly significant reduction in the rate of influenza-like illness symptoms in comparison to the control group. The observed reduction in rate of flu-like symptoms remained even after adjusting for gender, race/ethnicity, hand washing practices, sleep quality, and flu vaccination.
Non-pharmaceutical interventions such as hand washing and masks---especially in a pandemic flu outbreak---are critical to study because pharmaceutical interventions such as vaccinations and antivirals may not be available in sufficient quantity for preventing and controlling pandemic influenza outbreaks.
In February 2007, the Centers for Disease Control and Prevention and the U.S. Department of Health and Human Services in collaboration with other federal agencies, education, businesses, healthcare and private sectors developed an interim planning guide on the use of Non-Pharmaceutical Interventions (NPIs) to mitigate an influenza pandemic.
The measures include voluntary home quarantine, isolation and treatment of cases, social distancing, personal protection such as face masks and hand hygiene, and school dismissal.
"Although a few of these measures can be evaluated during seasonal influenza outbreaks, many are difficult or impossible to evaluate in advance of a pandemic," Monto said. "However, use of face masks and hand hygiene interventions can be evaluated now, during seasonal influenza outbreaks, which can provide concrete evidence for decision makers."
Further studies are needed to confirm whether mask use may be an effective means of reducing influenza in shared living settings. Since it was not possible to blind subjects, knowledge of the intervention may have influenced influenza-like symptom reporting and therefore the results of this study should be interpreted with caution, Aiello said.
"During year two of the study (2007-2008) a major outbreak of influenza took place," Aiello said. "Forthcoming studies will examine whether results observed during this more severe outbreak mirror those observed during the milder year one influenza season. Influenza virus identification will also be examined as an additional outcome."
Laura Bailey | EurekAlert!
Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)
The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
17.10.2017 | Life Sciences
17.10.2017 | Life Sciences
17.10.2017 | Earth Sciences