Those were the conclusions of a new study by Henry Ford Hospital researchers who examined the medical records of epilepsy surgery patients and conducted a telephone survey to determine their satisfaction with the results of the procedure.
"Overall, the great majority of patients, 92 percent of them, expressed satisfaction with undergoing epilepsy surgery," says Vibhangini S. Wasade, M.D., a Henry Ford Hospital neurologist and lead author of the study.
"Following surgery, more patients were able to drive, and those with favorable seizure outcomes were more likely to be employed full-time and less likely to be taking antidepressant medication," Dr. Wasade adds.
The research will be presented at the American Epilepsy Society's 67th Annual Meeting in Washington, DC, by Marianna Spanaki-Varelas, M.D., the study's co-author and division head of the Henry Ford Comprehensive Epilepsy Program.
Each of the patients in the study group underwent resective surgery, in which the affected portion of their brain is removed, to treat refractory partial epilepsy. Refractory epilepsy, which affects about a third of those with the seizure disorder, is a form that resists treatment with medications.
The condition can severely damage patients' quality of life, leaving them wary of their next unpredictable seizure, limiting their ability to work full-time or successfully attend school and sometimes causing seizure-related injuries.
In such cases, resective surgery is considered an effective treatment. The most common procedure – temporal resection – involves removing the affected portion of the temporal lobe.
In other instances, seizure surgery is extra-temporal, in which a portion of the brain outside the temporal lobes – including the frontal, parietal or occipital lobes – is removed.
Henry Ford researchers used its databases to identify patients who had epilepsy surgery from 1993 to 2011. Of those 420 patients, 253 were surveyed by telephone to determine their current seizure frequency, driving status, employment status and use of antidepressants.
Of the 253 patients surveyed:
82 patients (32 percent) were seizure free, and 189 (75 percent) had a favorable outcome.
Temporal resection was performed on 215 patients (85 percent) of the study group, with significant favorable outcomes.
Patients were more likely to be driving compared to before their surgery (51 percent versus 35 percent).
The difference in current full-time employment status was significantly higher in temporal resections compared to extra-temporal – (45 percent versus 26 percent).
Patients with favorable surgical outcomes were more likely to be driving (65 percent versus 11 percent), employed – (28 percent versus 8 percent), and less likely to be taking anti-depressants – (24 percent versus 47 percent), compared to those without favorable outcomes.
The other co-investigators of this study are Jason Schwalb, M.D., Rizwan Tahir, M.D., and Lonni Schultz, Ph.D., from Henry Ford Hospital, and Kost Elisevich, M.D., and Brien Smith, M.D., from Spectrum Health System.
Editors Note: Authors of this study will be available at a press briefing at 9am (EDT), Dec. 8, in the onsite pressroom, Room 209-A, Level 2 of the Walter E. Washington Convention Center. The call-in number for off-site journalists is 1-605-475-4000, passcode 521653#.
Dwight Angell | EurekAlert!
A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg
Urbanization to convert 300,000 km2 of prime croplands
27.12.2016 | Mercator Research Institute on Global Commons and Climate Change (MCC) gGmbH
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...
Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.
Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
16.01.2017 | Trade Fair News
16.01.2017 | Automotive Engineering
16.01.2017 | Life Sciences