Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Liver donations from living donors increase 42 percent after educational intervention

07.01.2010
Living liver donors share their stories -- more step forward to donate

A recent study found that living donation increased 42% and the number of individuals who presented for donation evaluation increased 74% at centers in New York. The surge in live donation and donor evaluation occurred after additional education was provided to liver transplant candidates.

Those candidates exposed to the peer-based intervention (education) reported significantly greater knowledge, greater likelihood to discuss donation and increased self-efficacy compared to those not exposed to the intervention. Details of the study are reported in the January 2010 issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases, published by Wiley-Blackwell.

According to the United Network for Organ Sharing (UNOS) as of January 30, 2009 there were 100,539 candidates on the waiting list in the U.S., with over 15,000 individuals in need of a liver transplant. UNOS also reported the number of deceased donors is decreasing from 6,650 donors in 2006 to 6,494 donors in 2007—a concerning fact for liver transplant candidates. Past studies have shown that the median wait time for a liver was 296 and 306 days (2005 and 2006, respectively). In New York State in 2008, there were 133 deaths on the liver waitlist, an increase of 16% over 2007. The critical shortage of deceased liver donors, a lack of broader national sharing, increased wait times and deaths on the wait list, all incentivize transplant programs to look to alternative ways to expand the pool of livers available for transplant.

At the time of the study and based on UNOS data, New York had 1,947 individuals on the liver wait list which represents 12% of candidates nationally. In 2006-2007, random samples of waitlisted candidates at five transplant centers in New York were selected to complete (pre-intervention) surveys. A second sample of waitlisted candidates completed post-intervention surveys in 2008. These surveys included questions about: length of time on waiting list, education level, ethnicity, age, if they received educational materials (and helpfulness of materials), if they had discussed living liver donation with loved ones and if they had any plans to do so and where else they may have learned about liver transplantation.

"Past studies have show waitlisted candidates concerns over donor safety coupled with their general lack of knowledge about organ donation created a reluctance on the part of candidates to discuss living donor liver transplantation (LDLT) with family and friends," said Samantha DeLair, Director, New York Center for Liver Transplantation and lead author of this study. "The intervention material we used included testimonials and self-report data from living donors to educate liver candidates about the impacts, both the positives and the challenges of living liver donation," added Ms. DeLair.

In New York all living liver donors are periodically surveyed to assess the individuals' health and quality of life post-donation. Educational material used in the study to educate liver candidates was derived from 44 survey respondents in 2004-2005. The content of the booklet and DVD focuses on donor responses regarding: the surgery, recovery after donation, costs of donation, employment issues, and life after donation. The educational material used in this study, "In Their Own Words – The Experiences of Living Liver Donors," may be accessed at www.nyclt.org/living_donor/.

Of the donors whose self-reports were used to create the educational material, 87% recommend seeking input of a former donor prior to donating. One anonymous donor gives this advice to individuals considering the option of LDLT, "Every decision is personal…get as much information as possible and speak to other donors."

There were 437 waitlisted candidates at pre-test who completed surveys and 338 individuals at post-test. Participants had a median age of 55 years with 63% male and 56% of the total sample was White, non-Hispanic. Most surveyed were either newly listed (26%) or had been on the list for greater than 1 year (50%). For those participants exposed to the educational intervention, 91% reported having a "fair amount" or "a lot" of knowledge regarding LDTL compared to 70% of the unexposed group.

This study also tracked the number of friends and family members who presented to the five transplant centers for further information, discussion, and if appropriate, comprehensive evaluation for LDLT. Results indicate there was a 74% increase in LDLT evaluations from 2006 to 2008 at the intervention sites. After the educational intervention, there was a 42% increase in the number of individuals who completed an evaluation and donated a liver graft.

"Our data is compelling given the gains in waitlist candidates' knowledge of LDLT and the increases in the number of individuals interested in using this transplantation procedure," concluded Ms. DeLair. "It is important to follow live donors post-donation both for the donors themselves and to provide waitlist patients and their loved ones with as much information as possible as they consider live donation for themselves."

Article: "A Peer-Based Intervention to Educate Liver Transplant Candidates about Living Liver Donation." Samantha DeLair, Thomas Hugh Feeley, Hyunjung Kim, Juan del Rio Martin, Leona Kim-Schluger, Dianne LaPointe Rudow, Mark Orloff, Patricia A. Sheiner, Lewis Teperman. Liver Transplantation; Published Online: December 30, 2009 (DOI10.1002/lt.21937); Print Issue Date: January 2010 http://www3.interscience.wiley.com/journal/123226251/abstract

This study is published in Liver Transplantation. Media wishing to receive a PDF of this article may contact medicalnews@wiley.com

Liver Transplantation is published on behalf of The American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Since the first application of liver transplantation in a clinical situation was reported more than twenty years ago, there has been a great deal of growth in this field and more is anticipated. As an official publication of the AASLD and the ILTS. Liver Transplantation delivers current, peer-reviewed articles on surgical techniques, clinical investigations and drug research — the information necessary to keep abreast of this evolving specialty. For more information, please visit http://www3.interscience.wiley.com/journal/106570021/home.

Wiley-Blackwell is the international scientific, technical, medical, and scholarly publishing business of John Wiley & Sons, with strengths in every major academic and professional field and partnerships with many of the world's leading societies. Wiley-Blackwell publishes nearly 1,500 peer-reviewed journals and 1,500+ new books annually in print and online, as well as databases, major reference works and laboratory protocols. For more information, please visit www.wileyblackwell.com or www.interscience.wiley.com

Dawn Peters | EurekAlert!
Further information:
http://www.wiley.com
http://www.interscience.wiley.com

Further reports about: LDLT Liver Transplant Living Lakes-Konferenz Transplantation liver

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Molecular volume control

22.08.2017 | Life Sciences

When fish swim in the holodeck

22.08.2017 | Life Sciences

Biochemical 'fingerprints' reveal diabetes progression

22.08.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>