This research points to a possible link between the pet food contamination that occurred in North America in 2007 and the recent adulteration of milk protein and resultant intoxication of thousands of babies from Asia.
The research described in the paper identifies the principal contaminants as melamine and cyanuric acid. Neither of these compounds is very toxic when administered alone; however, when given in combination, the two compounds form a virtually insoluble complex. This complex forms in the tubules of the kidney, blocking urine flow and causing renal failure.
The research in the paper was done in rats, but because the toxicity depends only on the two compounds being present in the kidney at the same time, is relevant to other species, including humans. The research presented in the paper also shows that the melamine-cyanuric acid complex is soluble in acid, suggesting that acidification of the urine in the distal tubules of the kidney may be a reasonable treatment option.
 Identification and Characterization of Toxicity of Contaminants in Pet Food Leading to an Outbreak of Renal Toxicity in Cats and Dogs, 106, no.1 (November 2008): 251-262, Roy L. M. Dobson*, Safa Motlagh*, Mike Quijano*, R. Thomas Cambron*, Timothy R. Baker*, Aletha M. Pullen*, Brian T. Regg*, Adrienne S. Bigalow-Kern*, Thomas Vennard*, Andrew Fix*, Renate Reimschuessel , Gary Overmann*, Yuching Shan* and George P. Daston*
Kirsty Luff | alfa
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University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
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Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
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