"According to the results of our study, participating in a high-impact activity, such as running, more than one hour per day at least three times a week appears associated with more degenerated cartilage and potentially a higher risk for development of osteoarthritis," said the study's senior author Thomas M. Link, M.D., professor of radiology and chief of musculoskeletal imaging at the University of California, San Francisco (UCSF). "On the other hand, engaging in light exercise and refraining from frequent knee-bending activities may protect against the onset of the disease."
Osteoarthritis is a degenerative joint disease that causes pain, swelling and stiffness. According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases, osteoarthritis is the most common form of arthritis and affects an estimated 27 million Americans over the age of 25.
For the study, the researchers recruited 132 asymptomatic participants at risk for knee osteoarthritis who were enrolled in the National Institutes of Health Osteoarthritis Initiative, as well as 33 age- and body mass index-matched controls. Study participants included 99 women and 66 men between the ages of 45 and 55. The participants were separated into three exercise and strength-training levels, based on their responses to the Physical Activity Scale for the Elderly (PASE) questionnaire. Exercise levels included sedentary, light exercisers and moderate to strenuous exercisers, strength-training groups included none, minimal and frequent. Knee-bending activities were also analyzed.
MRI exams revealed that light exercisers had the healthiest knee cartilage among all exercise levels, and patients with minimal strength training had healthier cartilage than patients with either no strength training or frequent strength training.
Moderate to strenuous exercise in women who did any amount of strength training was associated with higher water content and more degenerated collagen architecture in the knee.
"The results for this group indicate that moderate to strenuous exercise may accelerate cartilage degeneration, putting these women at even greater risk of developing osteoarthritis," said study coauthor Keegan K. Hovis, B.S., R.N., research associate in the Department of Radiology at UCSF.
In addition, the findings showed that frequent knee-bending activities, such as climbing up at least 10 flights of stairs a day, lifting objects weighing more than 25 pounds, or squatting, kneeling or deep knee bending for at least 30 minutes per day, were associated with higher water content and cartilage abnormalities.
According to Dr. Link, known risk factors for cartilage degeneration include excess weight, knee injuries, frequent knee bending and severe or strenuous physical activity.
"People can reduce their risk for osteoarthritis by maintaining a healthy weight and avoiding risky activities and strenuous exercise," he said. "Lower-impact sports, such as walking, swimming or using an elliptical trainer are likely more beneficial than high-impact sports, such as running or tennis."
"Our findings indicate that light exercise, particularly frequent walking, is a safer choice in maintaining healthy cartilage," Hovis added.
Other coauthors are Christoph Stehling, M.D., Jean-Baptiste Pialat, M.D., Michael C. Nevitt, Ph.D., M.P.H., and Charles E. McCulloch, Ph.D.
Note: Copies of RSNA 2010 news releases and electronic images will be available online at RSNA.org/press10 beginning Monday, Nov. 29.
RSNA is an association of more than 46,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. The Society is based in Oak Brook, Ill. (RSNA.org)
Editor's note: The data in these releases may differ from those in the published abstract and those actually presented at the meeting, as researchers continue to update their data right up until the meeting. To ensure you are using the most up-to-date information, please call the RSNA Newsroom at 1-312-949-3233.
For patient-friendly information on MRI, visit RadiologyInfo.org.
Linda Brooks | EurekAlert!
Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences