Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Late preterm births risk respiratory illness

28.07.2010
Babies born between 34 weeks and 37 weeks gestation are much more likely to have respiratory illness compared to infants born at full term, and their risk of respiratory illness decreases with each additional week of gestation until 38 weeks, researchers report.

The study, published in the July 28 issue of JAMA, was conducted by University of Illinois at Chicago researcher Dr. Judith Hibbard and colleagues from the Consortium on Safe Labor.

For neonates born at 34 weeks, the odds of respiratory distress syndrome (RDS) were increased 40-fold.

"Even at 37 weeks, babies were three times more likely to have respiratory distress syndrome compared to babies born at 39- or 40 weeks," said Hibbard, UIC professor of obstetrics and gynecology and lead author of the study.

Contrary to earlier research, the researchers did not find a significant increase in respiratory illnesses in babies born at 38 weeks, compared with babies born at 39 and 40 weeks gestation, after controlling for multiple factors. Data were collected from electronic medical records on 233,844 deliveries at 19 hospitals across the U.S. between 2002 and 2008.

Hibbard said concern has grown in recent years about the problems associated with late preterm birth and the increasing number of babies delivered early. Respiratory illnesses such as RDS, transient tachypnea, pneumonia and respiratory failure can lead to other problems such as longer hospitalization, the need for a ventilator or antibiotics, and issues with feeding and failure to gain weight.

Medical experts suspect that the increase in late preterm births may be due in part to "convenience" c-sections and induced deliveries that are done, in some cases, "without good medical reason," said Hibbard.

The researchers looked at all newborns 34 weeks or greater with respiratory problems admitted to neonatal intensive care units. Late preterm births were compared with full-term births for resuscitation, respiratory support and respiratory diagnosis.

Using a statistical model, the researchers examined infant respiratory illnesses at each gestational week, controlling for factors that influence respiratory outcomes including maternal medical conditions, length of labor and mode of delivery, and birth weight.

The study found that late preterm births accounted for 9 percent of all deliveries. Thirty-seven percent of late preterm infants were admitted to the neonatal intensive care unit, compared with 7 percent of term infants.

Overall, respiratory illness occurred in 9 percent of late preterm births in the study.

RDS was the most common respiratory illness, occurring in 11 percent of 34-week deliveries. Only 0.3 percent of 40-week deliveries had RDS.

Transient tachypnea, also called "wet lungs," was the second most common respiratory illness, occurring in 6.4 percent of 34-week deliveries, and decreasing to 0.3 percent at 39 weeks.

"The OB community needs to assess indications for induction of labor," said Hibbard, who hopes that this study will help clinicians to counsel their patients about the importance of not requesting medically unnecessary inductions.

Hibbard suggests that further prospective research needs to be conducted to determine if it may be useful to use steroids to promote fetal lung maturity beyond the current standard of 34 weeks or if it may be useful to use medications to stop premature labor in women beyond 34 weeks to maintain pregnancy longer.

Hibbard's UIC co-authors are Dr. Isabelle Wilkins, professor and director of maternal-fetal medicine, and Dr. Michelle Kominiarek, assistant professor of maternal-fetal medicine. The Consortium on Safe Labor includes researchers from 12 institutions (19 hospitals) who contributed data to study labor progression and Cesarean delivery.

The study was supported by the Intramural Research Program of the Eunice Shriver Kennedy National Institute of Child Health and Human Development, one of the National Institutes of Health.

Sherri McGinnis Gonzalez | EurekAlert!
Further information:
http://www.uic.edu

Further reports about: Hibbard RDS SAFE UIC health services preterm birth respiratory distress respiratory illness

More articles from Studies and Analyses:

nachricht Real-time feedback helps save energy and water
08.02.2017 | Otto-Friedrich-Universität Bamberg

nachricht The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Switched-on DNA

20.02.2017 | Materials Sciences

Second cause of hidden hearing loss identified

20.02.2017 | Health and Medicine

Prospect for more effective treatment of nerve pain

20.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>