Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Late preterm births risk respiratory illness

28.07.2010
Babies born between 34 weeks and 37 weeks gestation are much more likely to have respiratory illness compared to infants born at full term, and their risk of respiratory illness decreases with each additional week of gestation until 38 weeks, researchers report.

The study, published in the July 28 issue of JAMA, was conducted by University of Illinois at Chicago researcher Dr. Judith Hibbard and colleagues from the Consortium on Safe Labor.

For neonates born at 34 weeks, the odds of respiratory distress syndrome (RDS) were increased 40-fold.

"Even at 37 weeks, babies were three times more likely to have respiratory distress syndrome compared to babies born at 39- or 40 weeks," said Hibbard, UIC professor of obstetrics and gynecology and lead author of the study.

Contrary to earlier research, the researchers did not find a significant increase in respiratory illnesses in babies born at 38 weeks, compared with babies born at 39 and 40 weeks gestation, after controlling for multiple factors. Data were collected from electronic medical records on 233,844 deliveries at 19 hospitals across the U.S. between 2002 and 2008.

Hibbard said concern has grown in recent years about the problems associated with late preterm birth and the increasing number of babies delivered early. Respiratory illnesses such as RDS, transient tachypnea, pneumonia and respiratory failure can lead to other problems such as longer hospitalization, the need for a ventilator or antibiotics, and issues with feeding and failure to gain weight.

Medical experts suspect that the increase in late preterm births may be due in part to "convenience" c-sections and induced deliveries that are done, in some cases, "without good medical reason," said Hibbard.

The researchers looked at all newborns 34 weeks or greater with respiratory problems admitted to neonatal intensive care units. Late preterm births were compared with full-term births for resuscitation, respiratory support and respiratory diagnosis.

Using a statistical model, the researchers examined infant respiratory illnesses at each gestational week, controlling for factors that influence respiratory outcomes including maternal medical conditions, length of labor and mode of delivery, and birth weight.

The study found that late preterm births accounted for 9 percent of all deliveries. Thirty-seven percent of late preterm infants were admitted to the neonatal intensive care unit, compared with 7 percent of term infants.

Overall, respiratory illness occurred in 9 percent of late preterm births in the study.

RDS was the most common respiratory illness, occurring in 11 percent of 34-week deliveries. Only 0.3 percent of 40-week deliveries had RDS.

Transient tachypnea, also called "wet lungs," was the second most common respiratory illness, occurring in 6.4 percent of 34-week deliveries, and decreasing to 0.3 percent at 39 weeks.

"The OB community needs to assess indications for induction of labor," said Hibbard, who hopes that this study will help clinicians to counsel their patients about the importance of not requesting medically unnecessary inductions.

Hibbard suggests that further prospective research needs to be conducted to determine if it may be useful to use steroids to promote fetal lung maturity beyond the current standard of 34 weeks or if it may be useful to use medications to stop premature labor in women beyond 34 weeks to maintain pregnancy longer.

Hibbard's UIC co-authors are Dr. Isabelle Wilkins, professor and director of maternal-fetal medicine, and Dr. Michelle Kominiarek, assistant professor of maternal-fetal medicine. The Consortium on Safe Labor includes researchers from 12 institutions (19 hospitals) who contributed data to study labor progression and Cesarean delivery.

The study was supported by the Intramural Research Program of the Eunice Shriver Kennedy National Institute of Child Health and Human Development, one of the National Institutes of Health.

Sherri McGinnis Gonzalez | EurekAlert!
Further information:
http://www.uic.edu

Further reports about: Hibbard RDS SAFE UIC health services preterm birth respiratory distress respiratory illness

More articles from Studies and Analyses:

nachricht Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT

nachricht Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>