With the use of sophisticated mathematical modelling techniques, a mathematician at The Hong Kong Polytechnic University (PolyU) and his co-researchers have completed a study that explains the phenomenon of multiple waves of influenza pandemic in the last century.
Taking part in this advanced study is Dr Daihai He, Assistant Professor of PolyU's Department of Applied Mathematics. He has collaborated with four researchers in Canada to offer an explanation to the worst influenza pandemic in the history of mankind.
The research team found that behavioural response has the largest impact among three primary factors causing the waves, thus paving the way for future enhancement on control strategies to the spread of influenza virus.
The 1918 flu epidemic was one of the world's deadliest natural disasters, causing the death of hundred thousands of people. Influenza pandemic appears to be characterized by multiple waves of incidence in one year, but the mechanism that explains this phenomenon has so far been elusive.
In explaining the deadly pandemic, Dr Daihai He and his teammates have incorporated in their mathematical model three contributing factors for multiple waves of influenza pandemic in England and Wales: (i) schools opening and closing, (ii) temperature changes during the outbreak, and (iii) changes in human behaviour in response to the outbreak.
Dr He and the researchers further applied this model to the reported influenza mortality during the 1918 pandemic in 334 British administrative units and estimate the epidemiological parameters. They have used information criteria to evaluate how well these three factors explain the observed patterns of mortality. The results indicate that all three factors are important, but behavioural responses had the largest effect.
The findings have recently been published in the journal Proceedings of the Royal Society Biological Sciences (July 2013 Issue). Dr He's expertise in advanced mathematics and statistics has helped improve our understanding of the spread of influenza virus at the population level and lead to improved strategies to control and minimize the spread of influenza virus.Press contact: Dr Daihai He
Regina Yu | Research asia research news
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy