“Falls can now be added to the growing list of poor health outcomes associated with non-adherence to medication,” said lead author Sarah D. Berry, MD, MPH, a research scientist with the Institute for Aging Research at Hebrew SeniorLife in Boston. “Because non-adherence is common and easy to screen for, health care providers should discuss this subject with their patients.”
Berry and her co-authors are the first investigators to study the association between falls and medication adherence. The team used data gathered from subjects in the Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly of Boston (MOBILIZE Boston) Study, a community-based cohort of seniors recruited for the purpose of studying novel risk factors for falls. They examined responses from a total of 246 men and 408 women with an average age of 78. Between 2005 and 2008, 376 individuals in this group reported a total of 1,052 falls.
A participant was characterized as having low medication adherence if he or she answered yes to any of the following questions: Do you ever forget to take your medications? Are you careless at times about taking your medications? When you feel better do you sometimes stop taking your medications? Sometimes if you feel worse when taking your medication, do you stop taking it? High adherence was defined as a “no” answer to every question. In total, 48 percent of the respondents were classified as having low medication adherence.
Those in the low-adherence group experienced falls at an annual rate of 1.5 times that of the high adherence group. This association persisted after adjusting for other variables, including age, sex, cognitive function, and total number of medications.
The journal article’s authors were supported by the Hartford Geriatrics Health Outcomes Research Scholars Awards Program, the Hebrew Rehabilitation Center for the Aged/Harvard Research Nursing Home Program funded by the National Institutes of Health, and an unrestricted grant from Pfizer, Inc.
The Journals of Gerontology Series A: Biological and Medical Sciences is a refereed publication of The Gerontological Society of America (GSA), the nation's oldest and largest interdisciplinary organization devoted to research, education, and practice in the field of aging. The principal mission of the Society — and its 5,200+ members — is to advance the study of aging and disseminate information among scientists, decision makers, and the general public. GSA’s structure also includes a policy institute, the National Academy on an Aging Society, and an educational branch, the Association for Gerontology in Higher Education.
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