That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The study's results suggest that because infertility may be an identifiable risk factor for prostate cancer, early screening may be warranted in infertile men.
Research focusing on the number of children a man has have pointed to male fertility's potential associated with risk for prostate cancer. However, studies on the topic have generated conflicting results: some have found that men with children had a higher risk than childless men; some have found that men with fewer children had a higher risk than men with more children; still others failed to identify any association between the number of children fathered and a man's risk for prostate cancer.
Because the number of children a man has may not accurately reflect his ability to cause a pregnancy, Thomas Walsh, MD, MS, of the University of Washington in Seattle and his colleagues designed a more accurate study to evaluate the association between male infertility and prostate cancer. They studied the risk for prostate cancer in a group of 22,562 men evaluated for infertility from 1967 to 1998 in 15 California infertility centers. The incidence of prostate cancer in these men was compared with the incidence in a sample of men in the general population who were of similar ages and from similar geographic locations.
The researchers identified 168 cases of prostate cancer that developed in men who were evaluated for infertility. That number not significantly different from the expected rate (185 cases), suggesting that overall, men evaluated for infertility were not at a higher risk of being diagnosed with any type of prostate cancer compared with men in the general population. However, men who were evaluated and found to be infertile were 2.6 times more likely to be diagnosed with high grade prostate cancer than men who were evaluated but were found not to be infertile.
The authors say if these results are confirmed in other studies, it may be appropriate for infertile men to be considered for early prostate cancer screening, given their elevated risk for aggressive disease. They add that the results should stimulate research on possible common biological pathways underlying infertility and prostate cancer.
Article: "Increased risk of high grade prostate cancer among infertile men." Thomas J. Walsh, Michael Schembri, Paul J. Turek, June M. Chan, Peter R. Carroll, James F. Smith, Michael L. Eisenberg, Stephen K. Van Den Eeden, and Mary S. Croughan. Cancer; Published Online: March 22, 2010 (DOI: 10.1002/cncr.25075).
Author Contact: To arrange an interview with Dr. Walsh, please contact Mary Guiden, Media Relations Manager, Health Sciences at the University of Washington on +1 206.616.3192 or firstname.lastname@example.org
David Sampson | EurekAlert!
Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT
Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
07.12.2016 | Health and Medicine
07.12.2016 | Life Sciences
07.12.2016 | Health and Medicine