Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Inexpensive rinsing effective at reducing post-op infection following joint replacement surgery

18.02.2011
Inexpensive Rinsing an Effective Means of Reducing Post-Operative Infection Following Total Joint Replacement Surgery

A rinsing technique with betadine that costs just a little over one dollar per patient may significantly reduce the infection rate following total knee and hip joint replacement surgery according to a study by researchers at Rush University Medical Center.

The study, presented at the American Association of Orthopedic Surgeons 2011 Annual Meeting, found that a three minute diluted betadine lavage combined with painting of the skin with a 10% betadine solution prior to surgical closure nearly eliminated early deep post-operative infection.

Deep periprosthetic joint infection is a rare but devastating complication associated with total joint replacement. Despite aseptic techniques, careful skin preparation and prophylactic antibiotics, deep infections still occur with a prevalence ranging from 0.3% to 1.9%.

Previous research has shown that a diluted betadine lavage of the surgical wound prior to closure reduces the rate of post-operative infection in orthopedic, urologic, cardiovascular and general surgery but it has not been previously studied in total joint arthroplasty.

“Betadine is safe, inexpensive, simple to use, and readily available within most operating rooms,” said study author Dr. Craig Della Valle, associate professor of orthopedic surgery at Rush. “In addition, betadine is effective on many types of bacteria including methicillin-resistant Staphylococcus Aureus (MRSA).

Researchers implemented a protocol for primary total knee and total hip arthroplasty in which the wound is soaked with the diluted betadine solution for three minutes following implantation of the prosthetic components. This is followed by a pulsating lavage of normal saline without antibiotics. Prior to final closure, betadine is applied to the skin surrounding the incision. Prior to this protocol, wounds were lavaged with normal saline only.

Acute post-operative deep infection was diagnosed in 18 out of the 1862 cases performed prior to the initiation of the betadine lavage protocol and in only one of the 688 total joint arthroplasties following initiation of this protocol; a reduction of the infection rate from 0.97% to 0.15%. There were no side complications associated with the treatment.

The study authors caution there are some limitations to the study. Changes in the surgeon’s technique occurred over the time of the study, and it was not feasible to determine the impact of these changes on the rate of infection. These included variations in the incision size, suture material, and type of skin sealant.

Kim Waterman | EurekAlert!
Further information:
http://www.rush.edu

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>