High-intensity exercise can help stable heart transplant patients reach higher levels of exercise capacity, and gain better control of their blood pressure than moderate intensity exercise, investigators report in a new study published in the American Journal of Transplantation.
Recent research shows that high-intensity interval exercise—training for a few minutes at close to the maximum heart rate—is safe and more efficient than moderate exercise for improving exercise capacity in different groups of patients with heart disease.
Researchers led by Christian Dall, PhD fellow, MSc, of the Bispebjerg Hospital at the University of Copenhagen, Denmark, investigated whether people who have received a new heart gain similar benefits from high-intensity interval training, or whether they should exercise at moderate intensity as currently recommended.
The team compared the effects of 12 weeks of high-intensity interval training versus continued moderate training in 16 stable heart transplant recipients who had been living with their new heart for more than one year.
The trial revealed that high-intensity interval training is safe in heart transplant patients, and the effect on exercise capacity and blood pressure control is superior to moderate intensity training. VO2 max, or maximal oxygen uptake, increased by 17 percent in patients performing high-intensity interval training compared with 10 percent in patients performing continued moderate training.
Systolic blood pressure decreased significantly in patients in the high-intensity group, while it remained unchanged in patients in the moderate intensity group. Peak heart rate also increased in the high-intensity group but not in the moderate intensity group. Heart rate recovery improved in both groups.
"Today, people who have been given a new heart experience increased physical function, quality of life, and overall life span; however, most patients continue to have limitations in their physical function and reduced quality of life compared to the general population due to side-effects from anti-rejection medications and because heart rate regulation is impaired after heart transplantation," said Dall.
"The impaired heart rate response has been considered a hindrance for more demanding high-intensity training, but this new study documents that stable heart transplant recipients benefit from this type of training more than from the moderate training that has been recommended so far. Importantly, the training is also safe and well received by patients."
The findings may be especially encouraging for athletes who compete in the Transplant Games of America, whose most recent event was held earlier this month in Houston, and those training for upcoming summer and winter World Transplant Games.
In an accompanying report, investigators provide a summary of a two-day meeting held in April 2013 in Toronto, Canada, in which a group of clinicians, researchers, administrators, and patient representatives discussed key issues related to exercise in organ transplant recipients.
The attendees developed a list of top research priorities and a research agenda for exercise in solid organ transplant, which includes the need to conduct large multicenter intervention studies, standardize measures of physical function in clinical trials, examine the benefits of novel types of exercise, and assess the effects of exercise on measures such as immunity, infection, and cognition.
Evelyn Martinez | Eurek Alert!
Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Transparent electronics devices are present in today’s thin film displays, solar cells, and touchscreens. The future will bring flexible versions of such devices. Their production requires printable materials that are transparent and remain highly conductive even when deformed. Researchers at INM – Leibniz Institute for New Materials have combined a new self-assembling nano ink with an imprint process to create flexible conductive grids with a resolution below one micrometer.
To print the grids, an ink of gold nanowires is applied to a substrate. A structured stamp is pressed on the substrate and forces the ink into a pattern. “The...
A new Fraunhofer MEVIS method conveys medical interrelationships quickly and intuitively with innovative visualization technology
On the monitor, a brain spins slowly and can be examined from every angle. Suddenly, some sections start glowing, first on the side and then the entire back of...
Researchers at the U.S. Department of Energy's (DOE) Ames Laboratory have discovered an unusual property of purple bronze that may point to new ways to achieve high temperature superconductivity.
While studying purple bronze, a molybdenum oxide, researchers discovered an unconventional charge density wave on its surface.
Munich Physicists have developed a novel electron microscope that can visualize electromagnetic fields oscillating at frequencies of billions of cycles per second.
Temporally varying electromagnetic fields are the driving force behind the whole of electronics. Their polarities can change at mind-bogglingly fast rates, and...
Breakup of continents with two speed: Continents initially stretch very slowly along the future splitting zone, but then move apart very quickly before the onset of rupture. The final speed can be up to 20 times faster than in the first, slow extension phase.phases
Present-day continents were shaped hundreds of millions of years ago as the supercontinent Pangaea broke apart. Derived from Pangaea’s main fragments Gondwana...
15.07.2016 | Event News
15.07.2016 | Event News
11.07.2016 | Event News
26.07.2016 | Information Technology
26.07.2016 | Health and Medicine
26.07.2016 | Physics and Astronomy