Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Henry Ford Hospital study: Less prep needed for colonoscopy

03.05.2010
Researchers at Henry Ford Hospital may have found a better way to prep patients for colonoscopy procedures so they no longer need to drink a gallon of prescribed fluids prior to the procedure.

The study found that patients who took a pill that is FDA-approved for chronic constipation as part of the colonoscopy prep only needed to drink half of the liquid previously required to cleanse the bowels.

While the combination did not improve polyp detection during the colonoscopy, researchers say it led to improved bowel preparation quality and was better tolerated by patients than the liquid mix of polyethylene glycol (PEG) and electrolytes alone.

"Most people say they don't want to have a colonoscopy because they find the preparation intolerable," says Chetan Pai, D.O., a Henry Ford Hospital gastroenterologist and lead author of the study.

"If physicians are able to offer a better way to prep, I think this will encourage more people to get the colonoscopies that may save their lives."

He explains that approximately 90 percent of colon cancer occurs in people over age 50, but these older adults tend to have difficulty drinking a gallon of electrolytes in preparation for the colonoscopy.

Study results will be presented May 2 at Digestive Diseases Week in New Orleans.

According to the National Cancer Institute, in 2009, more than 146,000 new cases of colon and rectal cancer were diagnosed and nearly 50,000 people died from the disease. However, colon cancer is one of the most preventable forms of cancer because if it is found early through a colonoscopy screening test, it can be stopped before it has spread.

The constipation drug lubiprostone – a chloride pump activator in tablet form – has been used anecdotally in patients unable to tolerate drinking a full gallon of PEG and electrolytes as part of the bowel cleansing preparation for colonoscopy.

To test the effectiveness of lubiprostone as part of colonoscopy prep, Henry Ford conducted a randomized, double-blind and placebo-controlled study of 126 patients.

Researchers looked at the tolerability of the combination of lubiprostone and electrolytes, as well as electrolytes alone, and whether it was possible to reduce the volume of electrolytes required for colon cleansing.

The study was funded by Sucampo Pharmaceuticals, Inc., the manufacturer of lubiprostone.

Maria Seyrig | EurekAlert!
Further information:
http://www.hfhs.org

More articles from Studies and Analyses:

nachricht Drone vs. truck deliveries: Which create less carbon pollution?
31.05.2017 | University of Washington

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>