Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Global blueprint to treat childhood cancer

02.12.2008
Professor Andy Pearson, scientist at The Institute of Cancer Research and the Royal Marsden Hospital has co-chaired an international study to develop a global blueprint for the treatment of the most common childhood cancer - neuroblastoma, which affects an estimated 11,000 children each year worldwide.

The 25 country report has led to the creation of the International Neuroblastoma Risk Group Classification System, with the results published in two papers in the Journal of Clinical Oncology today.

Professor Pearson, alongside co-author Professor Susan Cohn at the University of Chicago are extremely optimistic about improving standards of care for all neuroblastoma patients. Professor Andrew Pearson comments:

“This tailored strategy will hopefully replace the existing ‘one size fits all’ approach utilised across the world. It streamlines the process for identifying what stage the disease is at and how aggressive it is, and clearly identifies how much treatment each child should receive.”

“In this way, we hope that children with neuroblastoma will receive the best possible chance of a cure, keeping the level of treatment and the associated side-effects to a minimum.”

The new strategy will be used by the International Neuroblastoma Risk Group (INRG) which represents paediatric oncologists treating neuroblastoma patients treated in Europe, Japan, the USA, Canada, and Australia.

Survival rates overall for children with cancer have improved dramatically in recent years. However, more than half of children with neuroblastoma will present the aggressive, high-risk disease, which is more likely to relapse and is linked with a poor rate of recovery.

“How neuroblastoma attacks the body varies dramatically in each patient and, up until now, it has been difficult to accurately predict the progression of the disease. With these systems, we will be able to choose appropriate treatments based on the evidence of relevant risk factors.” Professor Pearson says.

Neuroblastoma, a cancer of the developing nervous system, is one of the most common types of childhood cancers, causing 15 per cent of all childhood cancer deaths in the UK. Its different forms vary in severity: while some cases in young children disappear with minimal treatment, cases in older children can be relentlessly aggressive. Identifying the form is therefore crucial in planning appropriate treatment.

Bethany Hankin was diagnosed with aggressive neuroblastoma aged 18 months. Now 3 years old and in remission, her mother Katie Hankin is eager to see better information for doctors:

“The harsh reality is that neuroblastoma is one of the most aggressive childhood cancers, yet receives very little attention. During Bethany’s first course of treatment, we had been told parts of her diagnosis, but not the exact status of her disease. Neuroblastoma is such an unpredictable disease, any research that helps doctors make a more informed diagnosis sooner can only be a blessing for families.”

This new research was funded by the William Guy Forbeck Research Foundation and Little Heroes Paediatric Cancer Research Foundation, and offers clearer direction for diagnosis and risk assessment for clinicians on a global level.

The first of the two papers proposes the International Neuroblastoma Risk Group (INRG) classification system. The paper focuses on the personalisation of treatment by classifying neuroblastoma based on 13 factors.

The second paper replaces the current four stage system of diagnosis of neuroblastoma based on a new International Neuroblastoma Risk Group Staging System (INRGSS.)

Cathy Beveridge | alfa
Further information:
http://jco.ascopubs.org/
http://www.icr.ac.uk

Further reports about: Cancer Global blueprint INRG childhood cancer neuroblastoma risk factor

More articles from Studies and Analyses:

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

nachricht First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Designer cells: artificial enzyme can activate a gene switch

22.05.2018 | Life Sciences

PR of MCC: Carbon removal from atmosphere unavoidable for 1.5 degree target

22.05.2018 | Earth Sciences

Achema 2018: New camera system monitors distillation and helps save energy

22.05.2018 | Trade Fair News

VideoLinks
Science & Research
Overview of more VideoLinks >>>