No previous studies on the effect of genetic factors on the liability to disability retirement have been carried out. In the new research published today in the online peer-reviewed scientific journal PLoS ONE, a moderate genetic contribution to the variation of disability retirement due to any medical cause was found.
This 30-year follow-up study of 24 000 Finnish twins shows that genetic factors explained 36% of the variation in disability retirement due to any medical cause. The heritability estimate for disability pensions (DPs) due to other mental disorders than depression was 42%, due to musculoskeletal disorders 37% and due to cardiovascular diseases 48% indicating the importance of both genetic factors and different environmental exposures in the process of disability retirement.
Childhood environmental factors showed important effect on disability retirement due to depressive disorders
Interestingly, familial aggregation in DPs due to depressive disorders was best explained by the common environmental factors (28%) highlighting the important impact of early childhood environment on the development of depressive disorders and the risk of work disability in adulthood. However, the environmental factors not shared with family members showed increasing influence with increasing age at onset of disability retirement.
The novel scientific results of this study on the contribution of genetic factors to disability retirement, and insights from further studies on the complex gene-environment interactions and associations on the process of disability retirement during the life course, provide better focused tools for planning strategies to prevent work incapacity and early retirement among employees.
Paivi Lehtinen | alfa
Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University
New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
19.02.2018 | Materials Sciences
19.02.2018 | Materials Sciences
19.02.2018 | Life Sciences