Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

The Framingham Heart Study -- global impact, ongoing influence

07.07.2010
A special issue of Progress in Cardiovascular Diseases

Few medical investigations have had the impact of the Framingham Heart Study. This study, started in 1948, was designed as a cohort, observational study of cardiovascular disease, then recognized as a growing health threat but now has emerged as much more. The Framingham Heart study came to revolutionize thinking about cardiovascular disease, change the study of epidemiology, and even force the biostatistics community to develop multivariate analysis. In a special issue of Progress in Cardiovascular Diseases, leaders from around the world offer their views on the global impact of the Framingham Heart Study.

The issue includes 10 articles describing not only the historical background of the Framingham Study, but also some of the current public health programs around the world that grew out of Framingham. An interview with Dr. William Kannel, one of the principal investigators, provides a personal perspective on this monumental work.

From the insights developed over the 60+ years of this still-ongoing study, significant investigations show the continuing influence of Framingham. Dr. Pekka Puska describes the Finnish-North Karelia project, the most potent demonstration that behavioral alteration in lifestyle risk factors leads to improved cardiovascular outcomes. Dr. K. Srinath Reddy describes a wide-reaching public health initiative to combat an explosive emergence of cardiovascular disease in India and Southeast Asia. In another program based on the legacy of Framingham, Drs. Cother Hajat and Oliver Harrison describe their comprehensive survey of over 95% of the Abu Dhabi population to develop a nation-wide prevention program for both the native citizens and the immigrant communities.

"The now well-established risk factor concept, fundamental to prevention of CVD, originated from the Framingham study," commented Shanthi Mendis, MD, of the World Health Organization. "It generated seminal findings such as the effects of tobacco use, unhealthy diet, physical inactivity, obesity, raised blood cholesterol, raised blood pressure, and diabetes on CVD. When these findings were first published, these were novel cardiovascular risk factors, now they are the major focus for global and national prevention efforts for reducing the burden of CVD and other major noncommunicable diseases. The Framingham Heart Study has also been in the forefront of the development of cardiovascular risk prediction equations for assessment of absolute risk."

The true global impact of the Framingham Heart Study, according to Henry Greenberg, MD, St. Luke's Roosevelt Hospital Center, New York, NY, and Editor-in-Chief of Progress in Cardiovascular Diseases, is whether prevention works. "The final verdict on the efficacy and relevance of the Framingham Heart Study is the outcome. Altering behavioral or cultural or political determinants of risk does reduce the societal burden of CVD. In the United States, though lacking a top-down approach to public health, the dramatic fall in CVD mortality in the early 1960s when little but blood pressure control was available speaks to this. During the ensuing 40 years, about half of the 50% fall in CVD mortality is attributable to prevention and risk factor modification, the legacy of the Framingham Heart Study."

These articles appear in a special issue of Progress in Cardiovascular Diseases, The Global Impact of the Framingham Heart Study, Volume 53, Number 1, (July/August 2010), published by Elsevier.

Katrina Saling | EurekAlert!
Further information:
http://www.elsevier.com

More articles from Studies and Analyses:

nachricht Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT

nachricht Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Simple processing technique could cut cost of organic PV and wearable electronics

06.12.2016 | Materials Sciences

3-D printed kidney phantoms aid nuclear medicine dosing calibration

06.12.2016 | Medical Engineering

Robot on demand: Mobile machining of aircraft components with high precision

06.12.2016 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>