Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Folic acid found to improve vascular function in amenorrheic runners

11.05.2010
A study led by sports medicine researcher Anne Hoch, D.O. at The Medical College of Wisconsin in Milwaukee has found that oral folic acid may provide a safe and inexpensive treatment to improve vascular function in young female runners who are amenorrheic (not menstruating). The study is published in the May 2010 issue of Clinical Journal of Sport Medicine.

While the benefits for women leading an active lifestyle, including running, are profound and well-known, there are serious exercise-associated health risks. Young female athletes who do not eat enough to offset the energy they expend exercising can stop menstruating or develop irregular menses as a consequence.

Their resulting estrogen profile is similar to that of postmenopausal women who have low estrogen levels placing the young women at higher risk for early onset heart disease.

There are nearly three million girls in high school sports and approximately 23 million women who run at least six times a week. The prevalence of athletic-associated amenorrhea among these runners is now estimated at 44 percent. A previous study by Dr. Hoch conducted at Divine Savior Holy Angels High School, Milwaukee, revealed that 54 percent of the varsity athletes were currently or had a history of amenorrhea.

"The earliest sign of heart disease can be measured by reduced dilation in the brachial artery of the arm in response to blood flow. Reduced vascular dilation can limit oxygen uptake and affect performance," says Anne Hoch, D. O., the study's lead author. Dr. Hoch is a professor of orthopaedic surgery and director of the Froedtert & the Medical College Women's Sports Medicine Center.

The current study by Dr. Hoch's research team found that folic acid supplement improved blood flow-mediated dilation in the brachial artery which correlates with increased blood flow to the heart.

Both children and adults require folic acid to produce healthy red blood cells and prevent anemia. Folic acid, also known as vitamin B9, folacin and collate, is the form of the vitamin needed during periods of cell growth.

The researchers recruited 20 female college or recreational runners, ages 18 to 35, who were not on birth control pills and had been running at least 20 miles a week for the past 12 months. At the start of the study, women who were amenorrheic had reduced blood vessel dilation similar to postmenopausal women. Women who were menstruating were included in the control group. Both groups were given 10 mg. of folic acid per day for four weeks. Vascular function returned to normal in the amenorrheic women after folic acid supplementation. Despite supplementation, vascular function remained at normal levels in the control group.

More research is needed to determine the lowest optimal dose of folic acid for athletic amenorrhea which offers the maximum benefit. Folic acid supplementation is important because folic acid may not only decrease cardiovascular risks but also improve athletic performance for these women.

The study was partially funded by a grant from the Cardiovascular Center and the Department of Orthopaedic Surgery at the Medical College.

Toranj Marphetia | EurekAlert!
Further information:
http://www.mcw.edu

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Gold shines through properties of nano biosensors

17.08.2017 | Physics and Astronomy

Greenland ice flow likely to speed up: New data assert glaciers move over sediment, which gets more slippery as it gets wetter

17.08.2017 | Earth Sciences

Mars 2020 mission to use smart methods to seek signs of past life

17.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>