A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion.
"Easy access and good communication among surgeons, medical oncologists and reproductive endocrinologists is critical," said Lynn Westphal, MD, associate professor, department of obstetrics and gynecology, Stanford University School of Medicine, Stanford, CA.
Frequently, young women who are diagnosed with breast cancer must make difficult decisions about surgical treatment options as well as chemotherapeutic treatments that may permanently impair their fertility or delay childbearing. Advancements in reproductive medicine such as in vitro fertilization have benefited young women with breast cancer.
"The burden of facing premature menopause adds to the stress experienced by young cancer survivors," said Irene Wapnir, MD, FACS, associate professor, department of surgery, Stanford University School of Medicine. "Fertility preservation through cryopreservation of eggs or fertilized oocytes may be an important measure to offset these concerns and promote emotional well-being. Our study shows that these procedures, when expedited and appropriately timed, do not delay cancer treatment."
Researchers used the Stanford Cancer Center tumor registry to retrospectively identify 82 women younger than 40 years old who received adjuvant chemotherapy for breast cancer. Of the women identified, 19 underwent ovarian stimulation and oocyte retrieval, and 63 did not. The timing of fertility preservation, surgical intervention and chemotherapy were compared with the time intervals between diagnosis and treatment in the patients who did not undergo fertility preservation.The research team found that the median time from initial diagnosis to chemotherapy in women who underwent fertility preservation was 71 days (ranging from 45 days to 161 days) versus 67 days among those who did not (ranging from 27 days to 144 days; p
The mean age of the women who underwent fertility preservation was 33.7 years, and 84.2 percent had not previously given birth. Among women who did not undergo fertility treatment, the mean age was 35.2 years, and 25.4 percent had not previously given birth. The two groups were dissimilar with respect to stage of disease: 47.3 percent of patients in the fertility preservation group had node-negative disease, compared with 25.4 percent in the control group. Furthermore, 73.7 percent of the fertility preservation group had estrogen-positive tumors, compared with 65.1 percent of the control group.
About the American College of Surgeons
The American College of Surgeons is a scientific and educational organization of surgeons that was founded in 1913 to raise the standards of surgical practice and to improve the care of the surgical patient. The College is dedicated to the ethical and competent practice of surgery. Its achievements have significantly influenced the course of scientific surgery in America and have established it as an important advocate for all surgical patients. The College has more than 77,000 members and is the largest organization of surgeons in the world.
Sally Garneski | EurekAlert!
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
25.04.2017 | Physics and Astronomy
25.04.2017 | Materials Sciences
25.04.2017 | Life Sciences