They highlighted that at early stages of the disease those patients could recall recent memories, but also lasting memories from their youth which tend to disappear as dementia evolves. Mechanisms at the root of this autobiographical memory impairment result from storage deficits combined with faulty retrieval strategies.
Semantic dementia is a neurodegenerative disease characterized by a semantic memory breakdown; this type of memory concerns meanings and understandings about the world, e.g. "Paris is the capital of France" as well as personal semantics. Despite their important semantic deficits, these patients show preserved abilities concerning daily living activities and can recall recent specific personal events, with episodic details, at least at the beginning of the disease. This observation is interesting because it suggests that episodic autobiographical memory referring to both recent and old memories, particular to each individual at the source of personal continuity over time, is preserved in early SD.
Two groups of 7 patients each were studied. One group consisted of SD patients with mild cognitive impairment and the other consisted of patients with moderate cognitive impairment. An autobiographical memory test, called the TEMPau task, was used which assessed general and specific memories across the entire lifetime. Results indicated for the mild subgroup, preserved performances for the most recent time period and a relative preservation of a reminiscence bump, which concerns the surge of vivid and important self-defining episodic memories acquired between 18 and 30 years. In the moderate subgroup, performances were impaired whatever the time period including the most recent one. These results highlight that, with disease severity, episodic memories tend to vanish regardless of their recency.
The implications of these findings are particularly interesting from both theoretical and clinical viewpoints. First, they confirm that the relative preservation of episodic memories in early SD is not just a matter of recency, as frequently proposed. Second, they should provide new avenues on the development of specific methods of rehabilitation of new and old semantic concepts based on episodic autobiographical memory from the last 12 months and the reminiscence bump.
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy