A team of international researchers has discovered a new Ebola-like virus – Lloviu virus -- in bats from northern Spain. Lloviu virus is the first known filovirus native to Europe, they report in a study published in the journal PLOS Pathogens on Octobr 20th.
The study was a collaboration among scientists at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health, the Instituto de Salud Carlos III (ISCIII) in Spain, Roche Life Sciences, Centro de Investigación Príncipe Felipe, Grupo Asturiano para el Estudio y Conservación de los Murciélagos, Consejo Suerior de Investigaciones Científicas and the Complutense University in Spain.
Filoviruses, which include well-known viruses like Ebola and Marburg, are among the deadliest pathogens in humans and non-human primates, and are generally found in East Africa and the Philippines. The findings thus expand the natural geographical distribution of filoviruses.
"The study is an opportunity to advance the knowledge of filoviruses' natural cycle," said Ana Negredo, one of the first authors of the study.
Scientists at ISCIII analyzed lung, liver, spleen, throat, brain and rectal samples from 34 bats found in caves in Asturias and Cantabria, Spain, following bat die-offs in France, Spain and Portugal in 2002 affecting mainly one bat species.
They screened these samples for a wide range of viruses using the polymerase chain reaction, a molecular technique that allows scientists to amplify genetic material, and. detected a filovirus. Filoviruses include ebolaviruses and marburgviruses, two viruses associated with severe disease in humans and other primates..
CII scientists used high-throughput sequencing to characterize the virus' genome. When they compared it to other well-known filovirus genomes, they found that Lloviu virus represents a class of viruses distantly related to all ebolaviruses and that it may have diverged from ebolaviruses about 68,000 years ago.
"The detection of this novel filovirus in Spain is intriguing because it is completely outside of its previously described range. We need to ascertain whether other filoviruses native to Europe exist, and more importantly, if and how it causes disease," said Gustavo Palacios, the other first author of the study.
Filoviruses typically do not make bats sick, but because the team of researchers only detected Lloviu virus in bats that had died and whose tissues showed signs of an immune response, they think Lloviu may be a cause for concern. They also did not detect Lloviu virus in samples of almost 1,300 healthy bats.
Bats have important roles in plant pollination, spreading plant seeds and controlling insect populations, and pathogens that attack bat populations could have dramatic ecological and health-related consequences.
"The Lloviu virus discovery highlights how much we still need to learn about the world of emerging infectious diseases and the importance of global collaboration and the One Health initiative in addressing the challenge," said CII Director Dr. Ian Lipkin.
This research was funded by the Defense Threat Reduction Agency, USAID PREDICT, the RICET Network on Tropical Diseases and the Ministerio de Educación y Ciencia in Spain.
Stephanie Berger | EurekAlert!
Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT
Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
08.12.2016 | Physics and Astronomy
08.12.2016 | Health and Medicine
08.12.2016 | Life Sciences