Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Difficulties in diagnosing dementia type

31.05.2011
Many patients receive an incorrect dementia diagnosis. This is shown by a study carried out by neuropathology researchers in Lund, Sweden.

“It is true that we know of around 70 different types of dementia, but these findings are shocking. We believed more patients were diagnosed correctly when we began the study”, say researchers Elisabet Englund and Hans Brunnström at Lund University.

The study included 176 patients, the vast majority from the cities of Lund and Malmö. All of them have been examined at specialist geriatric psychiatry clinics during the period 1996–2006 and been diagnosed with some form of dementia. After the death of the patients, the researchers have studied their brains under a microscope and been able to establish precisely which type or types of dementia the patients suffered from.

In 49 per cent of cases, the clinical diagnosis agreed with the neuropathological. In 14 per cent of cases the diagnosis was partly in agreement, which to some extent could be explained by additional neurological damage following the clinical diagnosis. In 37 per cent of cases, an entirely different diagnosis was made after the patient’s death. The highest level of correct diagnoses was in patients with frontotemporal dementia, while the accuracy of the diagnoses was somewhat lower for patients with Alzheimer’s disease, vascular dementia or dementia with Lewy bodies.

“These are unexpected figures, particularly considering that these patients have been examined and diagnosed by specialists. There is currently no cure for these diseases, but we must be sure that the patient has received the correct diagnosis in order to able to prescribe the correct treatment, such as medication to slow the progression of the disease and/or treat symptoms”, says Dr Hans Brunnström, whose doctoral thesis includes the study.

“In addition, there is a hereditary factor in these diseases and so those with a family history of dementia should be able to find out which type of dementia their relatives have. It is therefore important that the diagnosis is correct”, says Associate Professor Elisabet Englund, highlighting aspects of patient examinations which need to be improved.

“We have a strong belief in having a team of specialists who make the diagnosis together. We strive to work in this way today, but there is still room for improvement.”

Elisabet Englund and Hans Brunnström also say that the neuropathology unit, which they represent, must provide better feedback to the clinic, while knowledge about these diseases must improve within primary care and the national guidelines that exist must be known to and followed by the broad medical community.

“Many of these types of dementia are difficult to assess, but it is important that a patient who has been diagnosed with dementia and has to live with the disease for six–eight years, and in some cases up to 20 years, is carefully assessed and receives the correct diagnosis.”

Hans Brunnström’s thesis is entitled Neuropathological findings and staging in dementia.

For more information:
Elisabet Englund: +46 46 173438, mobile: +46 707 744898, elisabet.englund@med.lu.se

Hans Brunnström: +46 46 174941, mobile: +46 702 703216, hans.brunnstrom@med.lu.se

Megan Grindlay | idw
Further information:
http://www.lu.se/o.o.i.s?id=12588&postid=1882978

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>