Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Decision guide reduced uncertainty over breast cancer prevention, study finds

16.04.2012
Tailored, web-based intervention helped women understand options

When women at high risk of breast cancer viewed a customized web-based decision guide about prevention options, they were more likely to make a choice about prevention and to feel comfortable with their choice, a new study finds.

Researchers developed a web-based tool called the Guide to Decide, which included general information about breast cancer and personalized information about an individual woman's five-year risk of breast cancer. The guide walked women through two medical options to prevent breast cancer: tamoxifen and raloxifene. Information was tailored to each woman's age and race, and included information on the benefits and risk of tamoxifen and raloxifene as well as how it would affect the woman's breast cancer risk.

The study looked at post-menopausal women ages 40-74 who were considered at high risk of breast cancer. Of the 1,012 women who participated, 690 were randomly assigned to view the decision guide. Participants were asked after viewing the guide and again three months later about whether they wanted to receive preventive treatment and how they felt about that decision.

Women who viewed the Guide to Decide reported significantly less uncertainty when deciding whether to take tamoxifen or raloxifene, and three months later they were more likely to have made a decision.

"Since the decision to use tamoxifen or raloxifene to prevent breast cancer is based on each woman's preferences, with no single right or wrong answer, the intervention enabled each woman to weigh the relative risks and benefits for herself and make a decision that aligned with her own values and preferences," says study first author Matthew (Mateo) P. Banegas, M.P.H., M.S., a doctoral candidate at the University of Washington and Fred Hutchinson Cancer Research Center. Banegas will present the findings April 14 at the Society of Behavioral Medicine annual meeting in New Orleans, La.

"Because the guide was web-based, women could access it in the comfort of their home or preferred setting, at their own pace, and with their family, friends or other support system around. In addition, tailoring the information meant it matched each woman's circumstances and was much more personal," says study senior author Angela Fagerlin, Ph.D., associate professor of internal medicine and co-director of the Center for Bioethics and Social Sciences in Medicine at the University of Michigan Medical School, and a research scientist at the VA Ann Arbor Center for Clinical Management Research.

Future research will look at how many risks and benefits can be presented to patients before they are overwhelmed by information and are not able to process it fully.

Breast cancer statistics: 229,060 Americans will be diagnosed with breast cancer this year and 39,920 will die from the disease, according to the American Cancer Society.

Additional authors: Jennifer B. McClure and Sarah Greene, Group Health Research Institute; William E. Barlow, Cancer Research and Biostatistics and Group Health Research Institute; Peter A. Ubel, Duke University; Dylan M. Smith, Stony Brook University; Brian Zikmund-Fisher, University of Michigan; Sharon H. Alford, Henry Ford Health System

Funding: National Institutes of Health (P50 CA101451), National Cancer Institute Biobehavioral Cancer Prevention and Control Training Program (R25CA092408) at the University of Washington, and the National Cancer Institute Center for Hispanic Health Promotion Training Program (1U54CA153502-01) at Fred Hutchinson Cancer Research Center

Disclosure: None

Reference: Society for Behavioral Medicine 33rd Annual Meeting and Scientific Sessions, April 11-14, 2012. "Assessing a web-based, tailored decision aid for women at high risk of breast cancer"

Resources:

U-M Cancer AnswerLine, 800-865-1125

U-M Comprehensive Cancer Center, http://www.mcancer.org

Clinical trials at U-M, http://www.UMClinicalStudies.org/cancer

Fred Hutchinson Cancer Research Center, http://www.fhcrc.org

Nicole Fawcett | EurekAlert!
Further information:
http://www.umich.edu

Further reports about: Banegas Cancer Decide Guide Hutchinson Medicine breast cancer health services

More articles from Studies and Analyses:

nachricht Antarctic Ice Sheet mass loss has increased
14.06.2018 | Technische Universität Dresden

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Temperature-controlled fiber-optic light source with liquid core

In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.

Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...

Im Focus: Overdosing on Calcium

Nano crystals impact stem cell fate during bone formation

Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

New cellular pathway helps explain how inflammation leads to artery disease

22.06.2018 | Life Sciences

When fluid flows almost as fast as light -- with quantum rotation

22.06.2018 | Physics and Astronomy

Exposure to fracking chemicals and wastewater spurs fat cell development

22.06.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>