Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cough may warn of danger for patients with lung-scarring disease

19.10.2011
A new analysis has found that coughing may signal trouble for patients with the lung-scarring disease known as idiopathic pulmonary fibrosis. The study, published in the journal Respirology, found that patients with the condition who also cough are more likely to develop advanced forms of the disease that may be life threatening.

When idiopathic pulmonary fibrosis develops, tissue deep in the lungs becomes thick and scarred, likely due to a response to an unknown substance. The condition affects approximately 100,000 individuals in the United States, and up to half die within three years of being diagnosed.

Almost all patients with idiopathic pulmonary fibrosis experience shortness of breath. The second most common symptom is cough. Shortness of breath is a known warning sign that a patient has a serious form of the disease, but little is known about the importance of cough.To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

The authors concluded that patients with idiopathic pulmonary fibrosis who cough may have a worse prognosis compared with patients who do not cough. While additional studies are needed to validate the results, patients who cough may benefit from closer monitoring and more aggressive treatments.

"These findings improve our understanding of cough in idiopathic pulmonary fibrosis," said Dr. Ryerson. "The reason for the association between cough and never having smoked is unknown, but may provide insight into the pathogenesis of cough in idiopathic pulmonary fibrosis and thus prompt future research in this area," he added.

Amy Molnar | EurekAlert!
Further information:
http://www.wiley.com

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>