Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cough may warn of danger for patients with lung-scarring disease

19.10.2011
A new analysis has found that coughing may signal trouble for patients with the lung-scarring disease known as idiopathic pulmonary fibrosis. The study, published in the journal Respirology, found that patients with the condition who also cough are more likely to develop advanced forms of the disease that may be life threatening.

When idiopathic pulmonary fibrosis develops, tissue deep in the lungs becomes thick and scarred, likely due to a response to an unknown substance. The condition affects approximately 100,000 individuals in the United States, and up to half die within three years of being diagnosed.

Almost all patients with idiopathic pulmonary fibrosis experience shortness of breath. The second most common symptom is cough. Shortness of breath is a known warning sign that a patient has a serious form of the disease, but little is known about the importance of cough.To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

The authors concluded that patients with idiopathic pulmonary fibrosis who cough may have a worse prognosis compared with patients who do not cough. While additional studies are needed to validate the results, patients who cough may benefit from closer monitoring and more aggressive treatments.

"These findings improve our understanding of cough in idiopathic pulmonary fibrosis," said Dr. Ryerson. "The reason for the association between cough and never having smoked is unknown, but may provide insight into the pathogenesis of cough in idiopathic pulmonary fibrosis and thus prompt future research in this area," he added.

Amy Molnar | EurekAlert!
Further information:
http://www.wiley.com

More articles from Studies and Analyses:

nachricht Drone vs. truck deliveries: Which create less carbon pollution?
31.05.2017 | University of Washington

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>