Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Confirmed: Study Pinpoints Molecular Mechanism that Causes Teens to be Less Sensitive to Alcohol than Adults

Researchers have known for years that teens are less sensitive than adults to the motor-impairing effects of alcohol, but they do not know exactly what is happening in the brain that causes teens to be less sensitive than adults. But now, neuropsychologists at Baylor University have found the particular cellular and molecular mechanisms underlying the age-dependent effect of alcohol in teens that may cause the reduced motor impairment.

The study appeared on-line in the journal Alcoholism: Clinical and Experimental Research. The study is the first to identify a mechanism underlying one of the main behavioral differences between adolescents and adults in their response to alcohol.

“This study is a significant advancement in understanding why adolescents are insensitive to alcohol and provides some insights into why teens might consequently consume alcohol to dangerous levels,” said Dr. Doug Matthews, a research scientist at Baylor who led the study. “This differential effect is not due to different blood-alcohol levels. Such reduced sensitivity in teens is troublesome considering that binge and heavy alcohol consumption increases throughout human adolescence and peaks at 21 to 25 years of age. Therefore understanding the mechanisms that underlie the reduced sensitivity to alcohol during adolescence is critical.”

Specifically, the Baylor researchers found the firing rate of a particular neuron called the cerebellar Purkinje neuron was insensitive to large alcohol doses in adolescent animal models, while the firing rate of those neurons was significantly depressed in adults. The spontaneous firing rate in adults from Purkinje neurons decreased approximately 20 percent, which researchers said indicates potential motor impairment. Adolescents, on the other hand, did show a slight motor impairment, however the firing rates from adolescent Purkinje neurons did not dramatically change in response to alcohol, and in fact showed a five percent increase in firing rate.

The Baylor researchers said this alcohol-induced reduction of spontaneous Purkinje neuron firing rates in adults could explain the greater sensitivity to alcohol’s motor impairing effects in adults compared to adolescents. However, there are likely to be contributions from other systems involved to cause thee different behavioral effects.

For more information, contact Matt Pene, assistant director of media communications at Baylor, at (254) 710-4656.

Matt Pene | Newswise Science News
Further information:

More articles from Studies and Analyses:

nachricht Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung

nachricht High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>