A study in the June 15 issue of the Journal of Clinical Sleep Medicine shows that the complaints of fatigue and tiredness in patients with obstructive sleep apnea (OSA) improved significantly with good adherence to continuous positive airway pressure (CPAP) therapy, suggesting that - like the symptom of excessive daytime sleepiness - these complaints are important symptoms of OSA.
Results indicate that good adherence to CPAP therapy for an average of five or more hours per night resolved baseline complaints of fatigue in 45 of 80 participants (56 percent), tiredness in 56 of 96 participants (58 percent) and sleepiness in 48 of 72 participants (67 percent); improvement of each symptom was significantly better among CPAP-adherent participants than among inadequately treated subjects. A baseline complaint of lack of energy also was resolved in 47 of 100 participants with good CPAP adherence, but this improvement failed to reach statistical significance when compared with inadequately treated participants.
According to senior investigator Ronald D. Chervin, M.D., M.S., of the Michael S. Aldrich Sleep Disorders Laboratory in Ann Arbor, Mich., physicians should consider the possibility of OSA as a treatable underlying cause not just for the complaint of sleepiness, but also for the chief complaints of fatigue, tiredness and lack of energy.
"We found that sleep apnea patients who used their CPAP regularly, in comparison to those who did not, had much greater success in reducing their fatigue, tiredness and sleepiness," he said. "This suggests that sleep apnea may be the cause of these symptoms, as it is a cause of sleepiness."
The study involved 313 OSA patients with an average age of 54.7 years; 178 (56.9 percent) were men. It compared 183 participants who reported using CPAP for an average of five or more hours per night with 96 subjects who either had no active treatment (55 subjects) or reported using CPAP for an average of less than five hours per night (41 subjects); 34 participants were excluded from the analysis because they received a treatment other than CPAP.
Compared with inadequately treated patients, participants who had good adherence to CPAP had a higher severity of OSA at baseline and lower self-reported sleepiness at follow-up. Both before and after treatment, women reported a complaint of lack of energy statistically more often than men.
According to the American Academy of Sleep Medicine, OSA is a sleep-related breathing disorder that involves a decrease or complete halt in airflow despite an ongoing effort to breathe. It occurs when the muscles relax during sleep, causing soft tissue in the back of the throat to collapse and block the upper airway. This leads to partial reductions (hypopneas) and complete pauses (apneas) in breathing that can produce abrupt reductions in blood oxygen saturation. Most people with OSA snore loudly and frequently, and they often experience excessive daytime sleepiness.
The authors suggest that their findings are in agreement with previous research demonstrating that CPAP adherence is associated with improvements in OSA symptoms, daytime sleepiness, cognitive impairments, blood pressure and quality of life.
A media fact sheet about OSA is available at http://www.aasmnet.org/Resources/FactSheets/SleepApnea.pdf ; information about OSA for patients and the public is available at http://www.sleepeducation.com/Disorder.aspx?id=7.
The Journal of Clinical Sleep Medicine (JCSM) contains published papers related to the clinical practice of sleep medicine, including original manuscripts such as clinical trials, clinical reviews, clinical commentary and debate, medical economic/practice perspectives, case series and novel/interesting case reports. In addition, the JCSM publishes proceedings from conferences, workshops and symposia sponsored by the American Academy of Sleep Medicine or other organizations related to improving the practice of sleep medicine
For a copy of the study, "Fatigue, Tiredness and Lack of Energy Improve with Treatment for OSA," or to arrange an interview with an AASM spokesperson, please contact Kelly Wagner, AASM public relations coordinator, at (708) 492-0930, ext. 9331, or email@example.com.
AASM is a professional membership organization dedicated to the advancement of sleep medicine and sleep-related research. As the national accrediting body for sleep disorders centers and laboratories for sleep related breathing disorders, the AASM promotes the highest standards of patient care. The organization serves its members and advances the field of sleep health care by setting the clinical standards for the field of sleep medicine, advocating for recognition, diagnosis and treatment of sleep disorders, educating professionals dedicated to providing optimal sleep health care and fostering the development and application of scientific knowledge.
Kelly Wagner | EurekAlert!
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences