Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Chronic Adolescent Nicotine Use Leads to Increased Susceptibility to Alcohol Withdrawal in Adulthood

04.03.2010
If you smoked cigarettes when you were a teen, new research indicates you might be more susceptible to the negative effects of alcohol withdrawal later in life.

Baylor University researchers have found that the chronic exposure to nicotine during adolescence in animal models caused a nicotine-induced change in brain development that led to increased vulnerability to alcohol withdrawal in adulthood. It is the first study to look at the combined effect of nicotine and alcohol exposure during the adolescent developmental period on the severity of a subsequent withdrawal from alcohol in adulthood.

The results are documented in the journal Alcohol.

“This study provides evidence that the developing adolescent brain is susceptible to the actions of nicotine and that the effects of that early exposure can result in changes that can be seen in adulthood,” said Dr. Jim Diaz-Granados, associate professor and chair of the department of psychology and neuroscience at Baylor, who helped lead the study. “Perhaps the most interesting finding is the group that was exposed to nicotine and alcohol during adolescence did not show the same effect as the nicotine-only group. This suggests that there is an interaction between the actions of the two drugs during this developmental period.”

The Baylor researchers exposed animal models to nicotine while others were given saline. In addition, half were given alcohol and the other half were given saline, with the treatment lasting approximately one week. After six weeks, all were exposed to 64 hours of alcohol. Upon removal, the researchers measured the severity of alcohol withdrawal. Those exposed to nicotine only during adolescence showed the most severe withdrawal symptoms, while those exposed to nicotine and alcohol during adolescence did not. Diaz-Granados said one outcome of alcohol withdrawal is nervous system hyperexcitability and those that had been exposed to nicotine during adolescent development suffered more severe alcohol withdrawal-related hyperexcitability.

“The results are another important indication that drug use during adolescent brain development can have long-term consequences as compared to drug use during adulthood,” Diaz-Granados said.

For more information, contact Matt Pene, assistant director of media relations at Baylor, at (254)710-4656.

Matt Pene | Newswise Science News
Further information:
http://www.baylor.edu/

More articles from Studies and Analyses:

nachricht Do microplastics harbour additional risks by colonization with harmful bacteria?
05.04.2018 | Leibniz-Institut für Ostseeforschung Warnemünde

nachricht Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

Im Focus: Basel researchers succeed in cultivating cartilage from stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...

Im Focus: Like a wedge in a hinge

Researchers lay groundwork to tailor drugs for new targets in cancer therapy

In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...

Im Focus: The Future of Ultrafast Solid-State Physics

In an article that appears in the journal “Review of Modern Physics”, researchers at the Laboratory for Attosecond Physics (LAP) assess the current state of the field of ultrafast physics and consider its implications for future technologies.

Physicists can now control light in both time and space with hitherto unimagined precision. This is particularly true for the ability to generate ultrashort...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Diamond-like carbon is formed differently to what was believed -- machine learning enables development of new model

19.04.2018 | Materials Sciences

Electromagnetic wizardry: Wireless power transfer enhanced by backward signal

19.04.2018 | Physics and Astronomy

Ultrafast electron oscillation and dephasing monitored by attosecond light source

19.04.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>