Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cancer patients who are separated when diagnosed have worse survival rates

25.08.2009
Among unmarried cancer patients, those who are separated at the time of diagnosis do not live as long as widowed, divorced, and never married patients.

That is the conclusion of a new study to be published in the November 1, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society. The authors of the study say its results suggest that the stress associated with marital separation may compromise an individual's immune system and lead to a greater susceptibility to cancer.

Research has shown that personal relationships have a significant role in physical health—specifically that good relationships are beneficial and poor relationships are deleterious. Also, many studies of cancer prognosis have found that patients who are married live longer than those who are single. However, little information is available regarding differences in survival among the various types of people who are unmarried.

To look for trends in cancer survival among patients who are separated, divorced, widowed, and never married, researchers led by Gwen Sprehn, Ph.D., of the Indiana University School of Medicine in Indianapolis analyzed data from the Surveillance Epidemiology and End Results (SEER) database, a population-based cancer registry in the United States.

The researchers assessed the 5 and 10 year survival rates of 3.79 million patients diagnosed with cancer between 1973 and 2004. They found that married patients had the highest 5 and 10 year survival rates, at 63.3 percent and 57.5 percent respectively. At the other end of the spectrum, separation carried the poorest survival outcome. Specifically, the 5 and 10 year survival rates for separated patients were 45.4 percent and 36.8 percent respectively. The 5 and 10 year survival rates of widowed patients were the next lowest, at 47.2 percent and 40.9 percent respectively; for divorced patients, the respective survival rates were 52.4 percent and 45.6 percent; and for never married patients, they were 57.3 percent and 51.7 percent.

The authors hypothesized that the stress of separation may compromise the immune system and thus create a greater vulnerability to cancer. While additional research is needed, the researchers say certain interventions might help patients today. For example, psychological interventions to reduce stress may impact the immune system and improve survival.

"Patients who are going through separation at the time of diagnosis may be a particularly vulnerable population for whom intervention could be prioritized," says Sprehn. "Identification of relationship-related stress at time of diagnosis could lead to early interventions which might favorably impact survival. Ideally, future research will study marital status in more detail over time and also address individual differences in genetic profile and biomarkers related to stress, immune, and cancer pathways in order to determine mechanisms which might underlie this possible critical period for cancer pathogenesis."

Article: "Decreased cancer survival in individuals separated at time of diagnosis: critical period for cancer pathophysiology?" Gwen C. Sprehn, Joanna E. Chambers, Andrew J. Saykin, Andre Konski, and Peter A. S. Johnstone. Cancer; Published Online: August 24, 2009 (DOI: 10.1002/cncr.24547); Print Issue Date: November 1, 2009.

David Sampson | EurekAlert!
Further information:
http://www.cancer.org

More articles from Studies and Analyses:

nachricht The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Molecular Force Sensors

20.09.2017 | Life Sciences

Producing electricity during flight

20.09.2017 | Power and Electrical Engineering

Tiny lasers from a gallery of whispers

20.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>