Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

BUSPH Study Observes Link Between Decongestant Use in Pregnant Women and Lower Risk of Preterm Birth

31.08.2010
A new study led by Boston University School of Public Health (BUSPH) epidemiologists has found that women who took over-the-counter decongestants during their pregnancies are less likely to give birth prematurely.

Preterm birth -- deliveries at less than 37 weeks' gestation­ -- is the leading cause of infant morbidity and mortality in developed countries, but its causes remain largely unknown, said Rohini Hernandez, the study's lead author and a doctoral candidate in epidemiology at BUSPH. In the United States, the rate of preterm delivery has increased from 9.5 percent in 1981 to 12.3 percent in 2008.

"Maybe this can provide some clues as to how to prevent preterm delivery," Hernandez said. "The more we can learn about what could potentially cause preterm birth would help our understanding in how to stop it."

The study, published online ahead of print in the journal Birth Defects Research Part A: Clinical and Molecular Teratology, found that women who took decongestants in their second or third trimesters had a roughly 58 percent reduced risk of preterm delivery compared to women who didn't use decongestants during their pregnancy. (The finding was observed only for women without preeclampsia.) The authors cautioned, however, that the findings do not necessarily imply a cause and effect relationship.

Decongestants are one of the most frequently used over-the-counter medications by pregnant women. Many, however, choose to not take any medications during their pregnancy to prevent potential harm to the developing fetus, Hernandez said.

"Medication use is a major concern for pregnant women and generally, when medications are found to have effects on the fetus, they're usually found to have adverse effects," Hernandez said. "This was surprising in that a potentially beneficial effect was found.

The researchers analyzed data from 3,271 live-born births by Massachusetts women, obtained between January 1998 and September 2008 as part of the longstanding Birth Defects Study, conducted by Boston University's Slone Epidemiology Center.

Approximately 6 percent of the study population delivered preterm, the authors wrote. Of that, 4.2 percent took decongestants while 6.7 percent did not. The women who took decongestants tended to be older, white, married, highly educated and have higher incomes.

The authors' findings supporting those from a 2006 Swedish study that found a link between prescription decongestant use and preterm delivery. Yet Hernandez said more research is needed to see if there is an actual cause and effect relationship between decongestant use and preterm birth and if so, what element in the decongestant is producing this outcome.

Co-authors on the study include Allen Mitchell, MD, professor of epidemiology and director of the Slone Epidemiology Center, and Martha Werler, DSc, MPH, professor of epidemiology.

Submitted by Elana Zak
ezak@bu.edu

Elana Zak | EurekAlert!
Further information:
http://www.bu.edu

More articles from Studies and Analyses:

nachricht Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)

nachricht The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>