Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Burden of diabetic ketoacidosis still unacceptably high

31.03.2014

CU researcher leads study on why 1 in 3 youth still presenting with DKA

Diabetic ketoacidosis (DKA), a life-threatening but preventable condition, remains an important problem for youth with diabetes and their families. Diabetic ketoacidosis is due to a severe lack of insulin and it is often the presenting symptom of type 1 diabetes. It can also be present at the onset of type 2 diabetes.

SEARCH for Diabetes in Youth, a multi-center, multiethnic study of childhood diabetes, is the largest surveillance effort of diabetes among youth under the age of 20 conducted in the United States to date. The study covers 5 locations across the country where about 5.5 million children live.

In a report in the April, 2014, issue of the Pediatrics, study investigators analyzed data from 5615 youth with type 1 and 1425 youth with type 2 diabetes newly diagnosed between 2002 and 2010. The study, led by Dana Dabelea, MD, PhD, professor and associate dean at the University of Colorado School of Public Health, shows that the frequency of DKA at diagnosis in U.S. youth with type 1 diabetes did not decline over the last 8 years, but remained high compared with other developed countries, with almost a third of all youth with type 1 diabetes presenting in DKA.

Rates were disproportionately high in children younger than 5 years of age, non-White racial/ethnic groups, youth without private health insurance and those with lower family income. Among youth with type 2 diabetes, DKA was much less common and decreased over time, suggesting improved detection or earlier diagnosis of diabetes.

Dabelea says "These data suggest that more needs to be done to begin reducing DKA rates in the future. Previous research suggests that increased community awareness of type 1 diabetes, including parental education and closer monitoring of signs and symptoms of diabetes, may be effective tools. In the U.S., improved health care access especially for underserved populations is also needed to reduce the observed health disparities."

SEARCH has estimated that there were at least 188,811 youth with diabetes in the U.S. in 2009: 168,141 with type 1 diabetes and 19,147 with type 2 diabetes. In the U.S. and worldwide, the incidence of type 1 diabetes in youth has been increasing by 3% to 4% per year, with limited estimates for type 2 diabetes except in minority populations in whom increased prevalence has also been reported.

###

The SEARCH study was funded by the Division of Diabetes Translation at the Centers for Disease Control and Prevention (CDC) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a part of the National Institutes of Health (NIH). It involves five research sites in the states of California (Jean M. Lawrence, ScD, principal investigator for Kaiser Permanente Southern California), Colorado (Dana Dabelea, MD, study co-chair and principal investigator at University of Colorado Denver), Ohio (Lawrence Dolan, MD, principal investigator for Cincinnati Children's Hospital), South Carolina (Elizabeth Mayer-Davis, PhD, study co-chair and principal investigator at University of North Carolina Chapel Hill) and Washington (Catherine Pihoker, MD, principal investigator for Seattle Children's Hospital). The central laboratory for the study is the Northwest Lipid Research Laboratories in Seattle, Washington (Santica Marcovina, PhD, principal investigator). The coordinating center is at the Division of Public Health Sciences at Wake Forest School of Medicine (Ronny Bell, PhD, principal investigator and Ralph B. D`Agostino Jr, co-principal investigator).

About the Colorado School of Public Health

The Colorado School of Public Health is the first and only accredited school of public health in the Rocky Mountain Region, attracting top tier faculty and students from across the country, and providing a vital contribution towards ensuring our region's health and well-being. Collaboratively formed by the University of Colorado Denver, Colorado State University, and the University of Northern Colorado, the Colorado School of Public Health provides training, innovative research and community service to actively address public health issues, including chronic disease, access to health care, environmental threats, emerging infectious diseases, and costly injuries.

Jackie Brinkman | EurekAlert!

Further reports about: Diabetic ketoacidosis Medicine diabetic diagnosis populations

More articles from Studies and Analyses:

nachricht Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung

nachricht High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: OLED microdisplays in data glasses for improved human-machine interaction

The Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP has been developing various applications for OLED microdisplays based on organic semiconductors. By integrating the capabilities of an image sensor directly into the microdisplay, eye movements can be recorded by the smart glasses and utilized for guidance and control functions, as one example. The new design will be debuted at Augmented World Expo Europe (AWE) in Berlin at Booth B25, October 18th – 19th.

“Augmented-reality” and “wearables” have become terms we encounter almost daily. Both can make daily life a little simpler and provide valuable assistance for...

Im Focus: Artificial Intelligence Helps in the Discovery of New Materials

With the help of artificial intelligence, chemists from the University of Basel in Switzerland have computed the characteristics of about two million crystals made up of four chemical elements. The researchers were able to identify 90 previously unknown thermodynamically stable crystals that can be regarded as new materials. They report on their findings in the scientific journal Physical Review Letters.

Elpasolite is a glassy, transparent, shiny and soft mineral with a cubic crystal structure. First discovered in El Paso County (Colorado, USA), it can also be...

Im Focus: Complex hardmetal tools out of the 3D printer

For the first time, Fraunhofer IKTS shows additively manufactured hardmetal tools at WorldPM 2016 in Hamburg. Mechanical, chemical as well as a high heat resistance and extreme hardness are required from tools that are used in mechanical and automotive engineering or in plastics and building materials industry. Researchers at the Fraunhofer Institute for Ceramic Technologies and Systems IKTS in Dresden managed the production of complex hardmetal tools via 3D printing in a quality that are in no way inferior to conventionally produced high-performance tools.

Fraunhofer IKTS counts decades of proven expertise in the development of hardmetals. To date, reliable cutting, drilling, pressing and stamping tools made of...

Im Focus: Launch of New Industry Working Group for Process Control in Laser Material Processing

At AKL’16, the International Laser Technology Congress held in May this year, interest in the topic of process control was greater than expected. Appropriately, the event was also used to launch the Industry Working Group for Process Control in Laser Material Processing. The group provides a forum for representatives from industry and research to initiate pre-competitive projects and discuss issues such as standards, potential cost savings and feasibility.

In the age of industry 4.0, laser technology is firmly established within manufacturing. A wide variety of laser techniques – from USP ablation and additive...

Im Focus: New laser joining technologies at ‘K 2016’ trade fair

Every three years, the plastics industry gathers at K, the international trade fair for plastics and rubber in Düsseldorf. The Fraunhofer Institute for Laser Technology ILT will also be attending again and presenting many innovative technologies, such as for joining plastics and metals using ultrashort pulse lasers. From October 19 to 26, you can find the Fraunhofer ILT at the joint Fraunhofer booth SC01 in Hall 7.

K is the world’s largest trade fair for the plastics and rubber industry. As in previous years, the organizers are expecting 3,000 exhibitors and more than...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Experts from industry and academia discuss the future mobile telecommunications standard 5G

23.09.2016 | Event News

ICPE in Graz for the seventh time

20.09.2016 | Event News

Using mathematical models to understand our brain

16.09.2016 | Event News

 
Latest News

Custom-tailored strategy against glioblastomas

26.09.2016 | Health and Medicine

Cooling buildings with solar heat

26.09.2016 | Power and Electrical Engineering

Chains of nanogold – forged with atomic precision

23.09.2016 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>