The study, published in the Investigative Ophthalmology & Visual Science journal (Intraocular Pressure and Corneal Biomechanics in an Adult British Population -- The EPIC-Norfolk Eye Study), reports the distribution and causes of eye pressure -- medically termed intraocular pressure (IOP).
According to the authors, researchers have long recognized that the clinical methods of assessing eye pressure have suffered from some inaccuracies, specifically as a consequence of the physical properties of the cornea. The EPIC-Norfolk study presents the first large-scale population-based measures of corneal biomechanics.
"Previously, a rather crude measure -- central corneal thickness -- was used as an index of corneal biomechanics," said author Paul J. Foster, MD, PhD, FRCS(Ed), of the University College London Institute of Ophthalmology, "We used a device which generates measures of corneal biomechanics in conjunction with IOP and attempts to 'correct' IOP for corneal physical properties."
Recruited between 1993 and 1997, the EPIC-Norfolk cohort was made up of approximately 25,000 predominantly Caucasian men and women aged 40 to 79 living in eastern England. From 2006 to 2010, a health examination was conducted to objectively assess various physical, cognitive and ocular characteristics of participants. The research team used a non-contact tonometer, the Ocular Response Analyzer, to obtain eye pressure and corneal biomechanical data from 4,184 study participants, now aged 48 to 91 years.
"The accurate measurements of IOP and interpretation of the results in terms of what is seen in the 'normal' population are cardinal pieces of information when healthcare professionals conduct routine eye examinations," said Foster. "We will be using our results to assess the validity of current glaucoma treatment guidelines, with respect to levels of risk attributed to specific levels of IOP."
The ARVO peer-reviewed journal Investigative Ophthalmology & Visual Science (IOVS) publishes results from original hypothesis-based clinical and laboratory research studies, as well as Reviews, Perspectives, and Special Issues. IOVS 2009 Impact Factor ranks No. 4 out of 45 among ophthalmology journals. The journal is online-only and articles are published daily.
The Association for Research in Vision and Ophthalmology (ARVO) is the largest eye and vision research organization in the world. Members include more than 12,500 eye and vision researchers from over 80 countries. ARVO encourages and assists research, training, publication and knowledge-sharing in vision and ophthalmology.
Katrina Norfleet | EurekAlert!
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
23.08.2017 | Life Sciences
23.08.2017 | Life Sciences
23.08.2017 | Physics and Astronomy