Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Breast-healthy lifestyle worthwhile, URMC study confirms

12.10.2010
Having a family history of breast cancer can lead some people to wonder if their risk is out of their control. However, a study of more than 85,000 postmenopausal women observed that regular physical activity, maintaining a healthy weight, and drinking less alcohol lowers breast cancer risk for women with, and without a family history of the disease.

The University of Rochester Medical Center study, published online Oct. 12, 2010, by the journal Breast Cancer Research, is good news for women who have a close relative with breast cancer and thus fear that no matter what they do, it won't matter, said lead author Robert E. Gramling, M.D., D.Sc., associate professor of Family Medicine, and Community and Preventive Medicine at URMC.

"It's important to note that a family history of breast cancer can arise in part due to shared unhealthy behaviors that have been passed down for generations," Gramling said. "Untangling the degree to which genes, environments, and behaviors contribute to the disease is difficult. But our study shows that engaging in a healthy lifestyle can help women, even when familial predisposition is involved."

Gramling analyzed data from the Women's Health Initiative Observational Study that began in 1993. The data included women ages 50 to 79, but excluded women with a personal history of breast cancer or with a close relative with early-onset (before age 45) breast cancer.

Researchers decided to exclude women in the latter group because they wanted to focus on whether the American Cancer Society recommendations on diet, exercise and alcohol consumption could plausibly influence disease rates. Women with relatives who were diagnosed prior to age 45 might have a more dominant genetic pattern so they were excluded, the study said.

The WHI-OS data divided women into two groups, those who had a family history of later-onset breast cancer (after age 45) and those who did not. Researchers further categorized the data, based on the degree to which women said they adhered to the ACS guidelines. "Complete adherence" equaled a minimum of 20 minutes of vigorous exercise at least five days a week, maintain a normal weight, and drink no more than one alcoholic beverage a day.

Finally, researchers looked at the cases of invasive breast cancer that arose during a mean follow-up period of 5.4 years. They assessed the relationship between rates of new invasive breast cancer cases, a family history of late-onset breast cancer, and whether either group was modified by the healthy lifestyle recommendations.

Among women with a family history who adhered to all three healthy behaviors, the rate of invasive breast cancer was 5.94 per 1,000 woman-years, compared with 6.97 per 1,000 woman-years among women who adhered to none of the behaviors, the study found.

Among women without a family history who adhered to all three healthy behaviors, the rate of invasive breast cancer was 3.51 per 1,000 woman-years compared to 4.67 per 1,000 woman-years for those who adhered to none.

The amount of risk reduced by adhering to the three health behaviors was the same for women with and without a family history.

Breast cancer is the most common form of cancer diagnosed in women, aside from non-melanoma skin cancer. About 15 percent of all postmenopausal women have a genetic predisposition to the disease.

Given the strong awareness of breast cancer and distress about inheritable risk, Gramling said, it is essential that scientists understand the actions women can take to reduce their risk.

The WHI program is supported by the National Heart, Lung and Blood Institute and the U.S. Department of Health and Human Services.

Leslie Orr | EurekAlert!
Further information:
http://www.urmc.rochester.edu

More articles from Studies and Analyses:

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

nachricht Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

From volcano's slope, NASA instrument looks sky high and to the future

27.04.2017 | Earth Sciences

Control of molecular motion by metal-plated 3-D printed plastic pieces

27.04.2017 | Materials Sciences

Move over, Superman! NIST method sees through concrete to detect early-stage corrosion

27.04.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>