Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Boys with urogenital birth defects are 33 percent more common in villages sprayed with DDT

26.10.2009
Babies born 5-9 years after official records showed mothers exposed to DDT spraying

Women who lived in villages sprayed with DDT to reduce malaria gave birth to 33 per cent more baby boys with urogenital birth defects (UGBD) between 2004 and 2006 than women in unsprayed villages, according to research published online by the UK-based urology journal BJUI.

And women who stayed at home in sprayed villages, rather than being a student or working, had 41 per cent more baby boys with UGBDs, such as missing testicles or problems with their urethra or penis.

The authors suggest that this is because they spent more time in homes where domestic DDT-based sprays are still commonly used to kill the mosquitos that cause malaria, even in areas where organised mass spraying no longer takes place.

Researchers led by the University of Pretoria in South Africa studied 3,310 boys born to women from the Limpopo Province, where DDT spraying was carried out in high-risk areas between 1995 and 2003 to control malaria. The study compared boys born to women in the 109 villages that were sprayed, with those born to women from the 97 villages that were not.

This showed that 357 of the boys included in the study – just under 11 per cent – had UGBDs. The incidence of UGBDs was significantly higher if the mother came from a sprayed village.

"If women are exposed to DDT, either through their diet or through the environment they live in, this can cause the chemical to build up in their body" explains lead author Professor Riana Bornman from the University's Department of Urology.

"DDT can cross the placenta and be present in breast milk and studies have shown that the residual concentration in the baby's umbilical cord are very similar to those in maternal blood.

"It has been estimated that if DDT exposure were to cease completely, it would still take ten to 20 years for an individual who had been exposed to the chemical to be clear of it. Our study was carried out on boys born between 2004 and 2006, five to nine years after official records showed that their mothers had been exposed to spraying.

"Records were not kept before 1995 in the Limpopo Province, but it is reasonable to assume that DDT was being used before that date to combat malaria.

"Although most countries have now banned the use of DDT, certain endemic malarial areas still use indoor residual spraying with DDT to decrease the incidence and spread of the disease, which is caused by mosquitoes."

The two-year study included 2,396 boys whose mothers had been exposed to DDT and 914 whose mothers had not.

A number of other factors were taken into account to rule out possible causes of the birth defects. These included smoking and drinking, the mother's age, how long she had lived in her village and her race. These all proved statistically insignificant.

The authors believe that their study highlights the importance of educating people in high-risk malaria areas about the dangers of DDT.

"The use of DDT has contributed to the success in reducing malarial transmission and malarial deaths in South and Southern Africa" says Professor Bornman.

"However, the present findings also strongly suggest that indoor residual spraying with DDT is associated with UGBDs in newborn boys.

"With global concerns about the effect of chemicals on health, and the possibility of malaria resurgence and spread as a result of climate change, all authorities should ensure that the general public, including those living under indoor residual spraying conditions, are aware of the possible health risks.

"Educating people living in the DDT-sprayed communities about ways of protecting themselves from undue DDT exposure needs to be carried out as a matter of extreme urgency.

"There must be long-term monitoring of possible environmental and human health impacts, particularly in those areas where DDT will be introduced as part of the fight against malaria.

"We are now carrying out further research to find out how indoor spraying using DDT-based products affects humans and how this risk can be reduced."

Notes to editors

DDT and urogenital malformations in newborn boys in a malarial area. Bornman et al. BJUI. Online publication 23 October 2009. doi: 10.1111/j.1464-410X.2009.09003.x

Established in 1929, BJUI is published 23 times a year by Wiley-Blackwell and edited by Professor John Fitzpatrick from Mater Misericordiae University Hospital and University College Dublin, Ireland. It provides its international readership with invaluable practical information on all aspects of urology, including original and investigative articles and illustrated surgery. www.bjui.org

Wiley-Blackwell is the international scientific, technical, medical and scholarly publishing business of John Wiley & Sons, with strengths in every major academic and professional field and partnerships with many of the world's leading societies. Wiley-Blackwell publishes over 1,400 peer-reviewed journals as well as 1,500+ new books annually in print and online, as well as databases, major reference works and laboratory protocols. For more information, please visit www.wileyblackwell.com or www.interscience.wiley.com

Annette Whibley | EurekAlert!
Further information:
http://www.interscience.wiley.com
http://www.bjui.org
http://www.wileyblackwell.com

Further reports about: BJUI DDT Malaria UGBD Wiley-Blackwell birth defect urogenital birth defects

More articles from Studies and Analyses:

nachricht Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)

nachricht The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>