Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Bottle-Fed Infants Most at Risk for Bisphenol A Ingestion, But Exposure Levels Well Below “Safe” Limits

10.03.2010
Study reviews more exposure pathways than previous surveys, also concludes additional research needed on production processes for canned soup, canned meat.

Swiss researchers examining exposure pathways for a common chemical used in plastic containers and linings of cans find infants have the highest estimated levels of Bisphenol A (BPA), with exposures falling with rising age. While estimated levels are well below the Tolerable Daily Intake (TDI) set by European authorities, the findings are important in that BPA is thought to impact human development and is classified as an endocrine disrupting chemical, potentially putting developing infants at risk, as well as fetuses if pregnant mothers are exposed.

The Swiss study examines 17 different sources of potential exposure across nine age/gender groups in the German/Swiss/Austrian population and found the most potentially exposed group is bottle-fed infants from 0-6 months of age. This group had estimated mean dose rates of nearly 0.8 micrograms per kilogram body weight per day, well below the TDI. However “it is of the same order of magnitude as recently reported concentrations that caused low-dose health effects in rodents,” according to the authors.

“In general humans in their developmental stages (fetus, infant, child) seem to be exposed more severely than adults,” wrote author Natalie von Goetz, Ph.D., senior scientist at the Swiss Federal Institute of Technology in Zurich, along with colleagues Matthias Wormuth, Martin Scheringer, and Konrad Hungerbuehler.

... more about:
»BPA »Bisphenol A »EPA pesticide »Risk Analysis »SRA »TDI

The European Union’s TDI for BPA is 50 micrograms per kilogram body weight per day, identical to the risk limit set by the U.S. Environmental Protection Agency (EPA). EPA and the U.S. Food and Drug Administration announced in January they are fast-tracking studies to clarify the research on low-dose effects of BPA exposure.

The study “Bisphenol A: How the Most Relevant Exposure Sources Contribute to Total Consumer Exposure” appears in the March issue of the journal Risk Analysis published by the Society for Risk Analysis.

The researchers detail the relative contributions of the most relevant exposure pathways to arrive at estimates of total consumer exposure, while past studies often focused on single pathways. To date, information on the relative contribution of the different pathways to total consumer exposure is lacking, but is key for managing substance-associated risks. Drawing on studies of how polycarbonate bottles and containers tend to leach more chemicals the more they are heated, the study determines from these and other research the main source of BPA for all consumer groups is food, although some is found in ambient air, drinking water from pipes sealed with epoxy, and as a result of dental surgery, among other sources. For adults, the highest dose comes from canned foods.

The highest uncertainty associated with the assessment lies in assumptions made on the consumption of packaged food. Consequently, the researchers focused on deriving realistic mean intake values from a range of different studies in order to first discriminate the different

BPA sources.

The authors call for more research on finding substitutes for these uses. The findings on dose rates for all consumers were found to closely correspond to global biomonitoring studies that measured BPA in humans, including surveys performed in the United States.

Risk Analysis: An International Journal is published by the nonprofit Society for Risk Analysis (SRA). SRA is a multidisciplinary, interdisciplinary, scholarly, international society that provides an open forum for all those who are interested in risk analysis. Risk analysis is broadly defined to include risk assessment, risk characterization, risk communication, risk management, and policy relating to risk, in the context of risks of concern to individuals, to public and private sector organizations, and to society at a local, regional, national, or global level.

Contact: Steve Gibb, 703.610.2441 Steve.Gibb@noblis.org or Lisa Pellegrin, 571.327.4868 or Lisa.Pellegrin@noblis.org to arrange an interview with the author(s). Note to editors: The complete study is available upon request from Lisa Pellegrin/Steve Gibb or here: http://www3.interscience.wiley.com/cgi-bin/fulltext/123268422/HTMLSTART

Steve Gibb | Newswise Science News
Further information:
http://www.sra.org

Further reports about: BPA Bisphenol A EPA pesticide Risk Analysis SRA TDI

More articles from Studies and Analyses:

nachricht The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig

nachricht Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Frictional Heat Powers Hydrothermal Activity on Enceladus

Computer simulation shows how the icy moon heats water in a porous rock core

Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Underwater acoustic localization of marine mammals and vehicles

23.11.2017 | Information Technology

Enhancing the quantum sensing capabilities of diamond

23.11.2017 | Physics and Astronomy

Meadows beat out shrubs when it comes to storing carbon

23.11.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>