Swiss researchers examining exposure pathways for a common chemical used in plastic containers and linings of cans find infants have the highest estimated levels of Bisphenol A (BPA), with exposures falling with rising age. While estimated levels are well below the Tolerable Daily Intake (TDI) set by European authorities, the findings are important in that BPA is thought to impact human development and is classified as an endocrine disrupting chemical, potentially putting developing infants at risk, as well as fetuses if pregnant mothers are exposed.
The Swiss study examines 17 different sources of potential exposure across nine age/gender groups in the German/Swiss/Austrian population and found the most potentially exposed group is bottle-fed infants from 0-6 months of age. This group had estimated mean dose rates of nearly 0.8 micrograms per kilogram body weight per day, well below the TDI. However “it is of the same order of magnitude as recently reported concentrations that caused low-dose health effects in rodents,” according to the authors.
“In general humans in their developmental stages (fetus, infant, child) seem to be exposed more severely than adults,” wrote author Natalie von Goetz, Ph.D., senior scientist at the Swiss Federal Institute of Technology in Zurich, along with colleagues Matthias Wormuth, Martin Scheringer, and Konrad Hungerbuehler.
The European Union’s TDI for BPA is 50 micrograms per kilogram body weight per day, identical to the risk limit set by the U.S. Environmental Protection Agency (EPA). EPA and the U.S. Food and Drug Administration announced in January they are fast-tracking studies to clarify the research on low-dose effects of BPA exposure.
The study “Bisphenol A: How the Most Relevant Exposure Sources Contribute to Total Consumer Exposure” appears in the March issue of the journal Risk Analysis published by the Society for Risk Analysis.
The researchers detail the relative contributions of the most relevant exposure pathways to arrive at estimates of total consumer exposure, while past studies often focused on single pathways. To date, information on the relative contribution of the different pathways to total consumer exposure is lacking, but is key for managing substance-associated risks. Drawing on studies of how polycarbonate bottles and containers tend to leach more chemicals the more they are heated, the study determines from these and other research the main source of BPA for all consumer groups is food, although some is found in ambient air, drinking water from pipes sealed with epoxy, and as a result of dental surgery, among other sources. For adults, the highest dose comes from canned foods.
The authors call for more research on finding substitutes for these uses. The findings on dose rates for all consumers were found to closely correspond to global biomonitoring studies that measured BPA in humans, including surveys performed in the United States.
Risk Analysis: An International Journal is published by the nonprofit Society for Risk Analysis (SRA). SRA is a multidisciplinary, interdisciplinary, scholarly, international society that provides an open forum for all those who are interested in risk analysis. Risk analysis is broadly defined to include risk assessment, risk characterization, risk communication, risk management, and policy relating to risk, in the context of risks of concern to individuals, to public and private sector organizations, and to society at a local, regional, national, or global level.
Contact: Steve Gibb, 703.610.2441 Steve.Gibb@noblis.org or Lisa Pellegrin, 571.327.4868 or Lisa.Pellegrin@noblis.org to arrange an interview with the author(s). Note to editors: The complete study is available upon request from Lisa Pellegrin/Steve Gibb or here: http://www3.interscience.wiley.com/cgi-bin/fulltext/123268422/HTMLSTART
Steve Gibb | Newswise Science News
Physics of bubbles could explain language patterns
25.07.2017 | University of Portsmouth
Obstructing the ‘inner eye’
07.07.2017 | Friedrich-Schiller-Universität Jena
Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers
Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...
Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.
At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...
3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects
A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
21.07.2017 | Event News
19.07.2017 | Event News
12.07.2017 | Event News
25.07.2017 | Physics and Astronomy
25.07.2017 | Earth Sciences
25.07.2017 | Life Sciences