Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Bottle-Fed Infants Most at Risk for Bisphenol A Ingestion, But Exposure Levels Well Below “Safe” Limits

Study reviews more exposure pathways than previous surveys, also concludes additional research needed on production processes for canned soup, canned meat.

Swiss researchers examining exposure pathways for a common chemical used in plastic containers and linings of cans find infants have the highest estimated levels of Bisphenol A (BPA), with exposures falling with rising age. While estimated levels are well below the Tolerable Daily Intake (TDI) set by European authorities, the findings are important in that BPA is thought to impact human development and is classified as an endocrine disrupting chemical, potentially putting developing infants at risk, as well as fetuses if pregnant mothers are exposed.

The Swiss study examines 17 different sources of potential exposure across nine age/gender groups in the German/Swiss/Austrian population and found the most potentially exposed group is bottle-fed infants from 0-6 months of age. This group had estimated mean dose rates of nearly 0.8 micrograms per kilogram body weight per day, well below the TDI. However “it is of the same order of magnitude as recently reported concentrations that caused low-dose health effects in rodents,” according to the authors.

“In general humans in their developmental stages (fetus, infant, child) seem to be exposed more severely than adults,” wrote author Natalie von Goetz, Ph.D., senior scientist at the Swiss Federal Institute of Technology in Zurich, along with colleagues Matthias Wormuth, Martin Scheringer, and Konrad Hungerbuehler.

... more about:
»BPA »Bisphenol A »EPA pesticide »Risk Analysis »SRA »TDI

The European Union’s TDI for BPA is 50 micrograms per kilogram body weight per day, identical to the risk limit set by the U.S. Environmental Protection Agency (EPA). EPA and the U.S. Food and Drug Administration announced in January they are fast-tracking studies to clarify the research on low-dose effects of BPA exposure.

The study “Bisphenol A: How the Most Relevant Exposure Sources Contribute to Total Consumer Exposure” appears in the March issue of the journal Risk Analysis published by the Society for Risk Analysis.

The researchers detail the relative contributions of the most relevant exposure pathways to arrive at estimates of total consumer exposure, while past studies often focused on single pathways. To date, information on the relative contribution of the different pathways to total consumer exposure is lacking, but is key for managing substance-associated risks. Drawing on studies of how polycarbonate bottles and containers tend to leach more chemicals the more they are heated, the study determines from these and other research the main source of BPA for all consumer groups is food, although some is found in ambient air, drinking water from pipes sealed with epoxy, and as a result of dental surgery, among other sources. For adults, the highest dose comes from canned foods.

The highest uncertainty associated with the assessment lies in assumptions made on the consumption of packaged food. Consequently, the researchers focused on deriving realistic mean intake values from a range of different studies in order to first discriminate the different

BPA sources.

The authors call for more research on finding substitutes for these uses. The findings on dose rates for all consumers were found to closely correspond to global biomonitoring studies that measured BPA in humans, including surveys performed in the United States.

Risk Analysis: An International Journal is published by the nonprofit Society for Risk Analysis (SRA). SRA is a multidisciplinary, interdisciplinary, scholarly, international society that provides an open forum for all those who are interested in risk analysis. Risk analysis is broadly defined to include risk assessment, risk characterization, risk communication, risk management, and policy relating to risk, in the context of risks of concern to individuals, to public and private sector organizations, and to society at a local, regional, national, or global level.

Contact: Steve Gibb, 703.610.2441 or Lisa Pellegrin, 571.327.4868 or to arrange an interview with the author(s). Note to editors: The complete study is available upon request from Lisa Pellegrin/Steve Gibb or here:

Steve Gibb | Newswise Science News
Further information:

Further reports about: BPA Bisphenol A EPA pesticide Risk Analysis SRA TDI

More articles from Studies and Analyses:

nachricht Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung

nachricht High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Innovative technique for shaping light could solve bandwidth crunch

20.10.2016 | Physics and Astronomy

Finding the lightest superdeformed triaxial atomic nucleus

20.10.2016 | Physics and Astronomy

NASA's MAVEN mission observes ups and downs of water escape from Mars

20.10.2016 | Physics and Astronomy

More VideoLinks >>>