Ben-Gurion University of the Negev (BGU) researchers reveal in a new, large-scale study that "normal" blood pressure at age 17 can still predict hypertension at early adulthood and that teenage boys are three to four times more likely to develop high blood pressure in early adulthood than girls.
According to the study published in Hypertension: Journal of the American Heart Association, the research team assessed how teenage boys and girls with normal blood pressure might progress into becoming young adults with hypertension. Currently, systolic blood pressures of 100 to 110 and even up to 120 are considered within the normal range for adolescents. Other traits like weight, height and body mass index (BMI) have a range of distribution that is considered "normal."
"Frequently called the 'silent killer,' hypertension is a major risk factor for heart disease and vascular diseases like stroke," explains researcher Dr. Assaf Rudich, an associate professor in the Department of Clinical Biochemistry at BGU. "It is increasing along with the obesity epidemic, but regrettably, young adults who are otherwise healthy frequently are not screened for becoming hypertensive."
The BGU researchers examined the development of blood pressure from adolescence to young adulthood in 23,191 boys and 3,789 girls from ages 17 to 42 by taking regular readings of their blood pressure and BMI of Israel Defense Forces personnel who were not hypertensive at age 17 in their initial evaluation before recruitment.
The study revealed two substantive findings:
In boys, there is a strong correlation between blood pressure and BMI at age 17. This means that while the blood pressure reading may be in the "normal range," there is a greater risk for hypertension when BMI is also evaluated.
The rate of progression to hypertension is higher in boys whose systolic blood pressure is 110 versus those whose blood pressure is 100.
For girls, only the sub-group considered obese had substantially higher risk of high blood pressure. The researchers believe that estrogen may protect against hypertension.
The study also confirmed several known observations:
Seventeen-year-old boys have higher blood pressure than their female counter parts.
Boys are three to four times more likely to develop hypertension as young adults and the higher the blood pressure value, even within the normal range, the higher is the risk for becoming hypertensive adults.
During a follow-up period with these adolescents, 14 percent or 3,810 people developed hypertension.
"Collectively, the study suggests that pediatricians caring for adolescents and physicians caring for young adults should be more aware of the need to monitor weight and blood pressure even when they are considered "normal," explains Dr. Iris Shai, an associate professor in the Department of Epidemiology in the Faculty of Health and Sciences. "For the individual person, a 'normal value' may still be associated with a significant elevated risk of disease when the BMI and sex of the patient is also considered."
Participants were part of the Metabolic, Lifestyle and Nutrition Assessment in Young Adults (MELANY) Study conducted by the Israel Defense Forces.
The Talpiot Medical Leadership Program, Chaim Sheba Medical Center, Tel-Hashomer Israel and the Israel Defense Forces Medical Corps funded the study.
About American Associates, Ben-Gurion University of the Negev
American Associates, Ben-Gurion University of the Negev (AABGU) plays a vital role in sustaining David Ben-Gurion's vision, creating a world-class institution of education and research in the Israeli desert, nurturing the Negev community and sharing the University's expertise locally and around the globe. With some 20,000 students on campuses in Beer-Sheva, Sede Boqer and Eilat in Israel's southern desert, BGU is a university with a conscience, where the highest academic standards are integrated with community involvement, committed to sustainable development of the Negev. For more information, please visit www.aabgu.org.
Andrew Laviin | EurekAlert!
Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University
New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy