Higher exposure to traffic-related air pollution (TRAP) dramatically increases the odds of readmission to the hospital for asthma – but only for white children, according to a new Cincinnati Children's Hospital Medical Center study.
The study shows that white children exposed to high levels of TRAP are three times more likely to be readmitted for asthma than white children with low TRAP exposure. Levels of TRAP exposure were not associated with increased risk of readmission of black children, despite their having overall higher rates of asthma readmission than white children.
The study is published in The Journal of Pediatrics.
"Although black children in our study had a higher rate of asthma readmission overall, TRAP exposure was not a discernible factor for these children. This suggests that other factors such as social stress or other environmental factors may be particularly relevant in this population," says Nicholas Newman, DO, a pediatrician at Cincinnati Children's and lead author of the study.
"For example, caregivers of black children reported significantly higher rates of psychological distress and were more likely to live in poorer housing conditions, with visible cockroaches or holes or cracks in the walls. These other factors may mask or overwhelm the impact of TRAP in black children."
The researchers studied 758 children between the ages of 1 and 16 admitted to Cincinnati Children's for asthma or wheezing. Fifty-eight percent were black and 32 percent white. Nineteen percent of all children were readmitted within the 12-month period.
TRAP is a complex mixture of chemicals and particles. In urban areas, diesel exhaust particles make up a substantial portion of particles, whose size is linked to their potential for causing health problems. These very small particles have greater potential to be inhaled into the lung, where they can cause swelling that blocks airways.
Exposure to TRAP in this study was estimated using a previously developed model that sampled ambient air at 27 sites in the Cincinnati area between 2001 and 2006. This model was used to estimate exposure for children enrolled in the study based on their home address.
Asthma is the most common chronic disease in children, affecting approximately 7.1 million children in the United States. The estimated annual cost of childhood asthma due to environmental factors, including air pollution is $2.2 billion.
"This study adds to the evidence that TRAP exposure worsens the health of children with asthma," says Robert Kahn, MD, MPH, associate director of general and community pediatrics at Cincinnati Children's and senior author of the study. "We hope that this study can inform public policy. It may also suggest ways to personalize patient care based on environmental risks."
The study is the most recent to be published as part of the Greater Cincinnati Asthma Risks Study (GCARS), which seeks to understand the causes of hospital readmission, particularly for low-income and minority children. The GCARS was funded by support from the National Institutes of Health (1R01AI88116) and the Center for Clinical and Translational Science and Training (NCRR/NIH ULI-RR026314-01).
Jim Feuer | EurekAlert!
Rutgers-led innovation could spur faster, cheaper, nano-based manufacturing
14.02.2018 | Rutgers University
New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg
Satellites in near-Earth orbit are at risk due to the steady increase in space debris. But their mission in the areas of telecommunications, navigation or weather forecasts is essential for society. Fraunhofer FHR therefore develops radar-based systems which allow the detection, tracking and cataloging of even the smallest particles of debris. Satellite operators who have access to our data are in a better position to plan evasive maneuvers and prevent destructive collisions. From April, 25-29 2018, Fraunhofer FHR and its partners will exhibit the complementary radar systems TIRA and GESTRA as well as the latest radar techniques for space observation across three stands at the ILA Berlin.
The "traffic situation" in space is very tense: the Earth is currently being orbited not only by countless satellites but also by a large volume of space...
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
23.03.2018 | Event News
19.03.2018 | Event News
16.03.2018 | Event News
23.03.2018 | Materials Sciences
23.03.2018 | Agricultural and Forestry Science
23.03.2018 | Physics and Astronomy