A groundbreaking study of couples led by Professor Eduardo Franco, Director of McGill University's Cancer Epidemiology Unit, in collaboration with a team of colleagues from McGill and Université de Montréal/Centre Hospitalier de l'Université de Montréal (CHUM), found more than half (56 per cent) of young adults in a new sexual relationship were infected with human papillomavirus (HPV). Of those, nearly half (44 per cent) were infected with an HPV type that causes cancer.
Dr. Ann Burchell, the Project Coordinator and a former PhD student and post-doctoral fellow with Dr. Franco at the Cancer Epidemiology Unit, conducted the HITCH Cohort Study (HPV Infection and Transmission in Couples through Heterosexual activity) to determine the prevalence of HPV infections among recently formed couples. This is the first large-scale study of HPV infection among couples early in their sexual relationships when transmission is most likely.
The results, published in the January 2010 issues of Epidemiology and Sexually Transmitted Diseases, also indicate there is a high probability of HPV transmission between partners. When one partner had HPV, the researchers observed that in 42 per cent of couples, the other partner also had the infection. Moreover, the researchers found that the presence of HPV in one partner was the strongest predictor of finding the same HPV type in the other partner. If one partner was infected with HPV, the other partner's chance of also being infected with the same HPV type increased over 50 times.
"These results build on our knowledge that HPV infection is very common among young adults, and underline the importance of prevention programs for HPV-associated diseases such as cervical cancer screening and HPV vaccination," said Dr. Ann Burchell. "Our results also suggest that HPV is an easy virus to get and to transmit. Our estimates of the HPV transmission probability will be of use to other researchers who use modeling to project the public health and economic impact of HPV vaccination strategies."
HITCH Cohort Study participants are young women attending university or college/CEGEP in Montreal, Quebec, and their male partners. New couples are defined as those who have been together for six months or less. Participants fill out questionnaires in which they answer questions about their sexual history and they also provide genital specimens for laboratory testing for the presence of HPV infection. Recruitment for the study is continuing.
"Our study is the first to investigate HPV transmission in a large number of new couples among young adults," says Dr. François Coutlée, a professor at the Université de Montréal Department of Microbiology and Immunology and researcher at the Centre Hospitalier de l'Université de Montréal where the HPV tests were analyzed. "The results suggest that many HPV transmissions occur at the start of new relationships, which reinforces the need for prevention."
HPV is sexually transmitted and causes cervical cancer as well as other cancers, including those of the vulva, vagina, anus, and penis. Although HPV viruses are very common – more than 70 per cent of women and men will have this type of infection at some point – the vast majority of infections are asymptomatic and last no more than one or two years. Fewer than 1 per cent of women who have HPV will get cervical cancer.
The Canadian Institutes for Health Research provided support for this study and for Dr. Franco's research program on HPV and cervical cancer, with supplementary and unconditional funding support by Merck-Frosst Canada Ltd. and Merck & Co. Ltd. Dr. Burchell was supported by a research studentship from the Canadian Cancer Society Research Institute and by a Richard H. Tomlinson doctoral fellowship to McGill University.
Allison Flynn | EurekAlert!
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
25.04.2017 | Earth Sciences
25.04.2017 | Life Sciences
25.04.2017 | Earth Sciences