“Because the only treatment for ischemic stroke must be given within a few hours after the first symptoms begin, people who wake up with stroke symptoms often can’t receive the treatment since we can’t determine when the symptoms started,” said study author Jason Mackey, MD, of the University of Cincinnati and a member of the American Academy of Neurology. “Imaging studies are being conducted now to help us develop better methods to identify which people are most likely to benefit from the treatment, even if symptoms started during the night.”
The study examined all cases of ischemic stroke in people age 18 and older seen in hospital emergency departments in the Greater Cincinnati/Northern Kentucky region over one year. The majority of strokes are ischemic strokes caused by blocked blood flow in the brain.
Of the 1,854 ischemic strokes in the study, 273, or 14 percent, were “wake-up strokes,” where the person woke up with stroke symptoms. By extrapolating that number to the general U.S. population, the researchers estimate that approximately 58,000 people in the United States go to the emergency department with a wake-up stroke in a year.
The researchers compared those with wake-up strokes to those who were awake when their stroke symptoms started. There were no differences between the two groups in terms of sex, whether they were married or were living with someone, and their stroke risk factors such as high blood pressure, diabetes, smoking or high cholesterol.
There were minor statistically significant differences in age and the severity of the stroke. People with wake-up strokes were an average of 72 years old, compared to 70 for non-wake-up strokes. Those with wake-up strokes had an average score of four on a test of stroke severity, compared to a three for those with non-wake-up strokes. Scores ranging from one to four indicate mild strokes.
The researchers also analyzed whether those with wake-up strokes would have been eligible for the clot-busting drug tissue plasminogen activator, or tPA, if the time of stroke onset had been available. Of the 273 wake-up strokes, at least 98 would have been eligible for treatment.
“This is a group of patients that should be a focus for future studies,” Mackey said. “It’s likely that some of these strokes occurred immediately prior to awakening, and people would benefit from treatment.”
The American Academy of Neurology, an association of 24,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.
For more information about the American Academy of Neurology, visit http://www.aan.com.VIDEO: http://www.youtube.com/AANChannel
Rachel L. Seroka | American Academy of Neurology
Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT
Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
06.12.2016 | Power and Electrical Engineering
06.12.2016 | Earth Sciences
06.12.2016 | Physics and Astronomy