Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

1 in 7 Strokes Occurs During Sleep, Many Go Without Clot-Busting Treatment

10.05.2011
Approximately 14 percent of all strokes occur during sleep, preventing many from getting clot-busting treatment, according to a study published in the May 10, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.

“Because the only treatment for ischemic stroke must be given within a few hours after the first symptoms begin, people who wake up with stroke symptoms often can’t receive the treatment since we can’t determine when the symptoms started,” said study author Jason Mackey, MD, of the University of Cincinnati and a member of the American Academy of Neurology. “Imaging studies are being conducted now to help us develop better methods to identify which people are most likely to benefit from the treatment, even if symptoms started during the night.”

The study examined all cases of ischemic stroke in people age 18 and older seen in hospital emergency departments in the Greater Cincinnati/Northern Kentucky region over one year. The majority of strokes are ischemic strokes caused by blocked blood flow in the brain.

Of the 1,854 ischemic strokes in the study, 273, or 14 percent, were “wake-up strokes,” where the person woke up with stroke symptoms. By extrapolating that number to the general U.S. population, the researchers estimate that approximately 58,000 people in the United States go to the emergency department with a wake-up stroke in a year.

The researchers compared those with wake-up strokes to those who were awake when their stroke symptoms started. There were no differences between the two groups in terms of sex, whether they were married or were living with someone, and their stroke risk factors such as high blood pressure, diabetes, smoking or high cholesterol.

There were minor statistically significant differences in age and the severity of the stroke. People with wake-up strokes were an average of 72 years old, compared to 70 for non-wake-up strokes. Those with wake-up strokes had an average score of four on a test of stroke severity, compared to a three for those with non-wake-up strokes. Scores ranging from one to four indicate mild strokes.

The researchers also analyzed whether those with wake-up strokes would have been eligible for the clot-busting drug tissue plasminogen activator, or tPA, if the time of stroke onset had been available. Of the 273 wake-up strokes, at least 98 would have been eligible for treatment.

“This is a group of patients that should be a focus for future studies,” Mackey said. “It’s likely that some of these strokes occurred immediately prior to awakening, and people would benefit from treatment.”

The American Academy of Neurology, an association of 24,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson’s disease and epilepsy.

For more information about the American Academy of Neurology, visit http://www.aan.com.

VIDEO: http://www.youtube.com/AANChannel
TEXT: http://www.aan.com/press
TWEETS: http://www.twitter.com/AANPublic

Rachel L. Seroka | American Academy of Neurology
Further information:
http://www.aan.com

More articles from Studies and Analyses:

nachricht The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung

nachricht A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>