Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Novel blood test for the early detection of oral, prostate and breast cancer

The likelihood for successful treatment of a cancer is fundamentally linked to an early diagnosis of the condition.

For this, it is essential to provide tests that allow early detection of cancer without the need of a tissue sample, and thus drastically improve the prognosis of the patients and their chance of a cure. Currently established cancer diagnostics either identify the disease too late or are unreliable, resulting in false positives, which can unsettle patients.

For instance, measuring PSA-levels for prostate cancer detection and mammographies for breast cancer prevention can provide false positive results without acute malignancies being found. Additionally, currently no blood test is available for oral cancer.

A novel blood test for the detection of cancer has been clinically assessed in a collaborative study between the university hospital Tuebingen, the German Cancer Research Center in Heidelberg, and the Clemenshospital of the university hospital muenster. This blood test utilizes the immune system; specifically the activity of macrophages, a type of white blood cell that scavenges tumor cells.

Using laser-based detection methods of tumor material within these scavenger cells, also known as EDIM (epitope detection in monocytes)-technology, it is now possible to discover the presence of tumor cells in small blood samples. This has allowed the early detection of oral, prostate, and breast cancer as well as relapses in patients by the EDIM-technology. Thus, this technology is also suitable for monitoring therapeutic efficacy. The results of this study represent an important hallmark in cancer detection, driven by the improved accuracy of the EDIM-blood test compared to previously established test methodologies.


A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells
Martin Grimm, Steffen Schmitt, Peter Teriete, Thorsten Biegner, Arnulf Stenzl, Jörg Hennenlotter, Hans-Joachim Muhs, Adelheid Munz, Tatjana Nadtotschi, Klemens König, Jörg Sänger, Oliver Feyen, Heiko Hofmann, Siegmar Reinert and Johannes F Coy
BMC Cancer 2013, 13:569 - doi:10.1186/1471-2407-13-569
Universitätsklinikum Tübingen
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
Priv.-Doz. Dr. Dr. Martin Grimm
Osianderstr. 2-8, 72076 Tübingen

Dr. Ellen Katz | idw
Further information:

More articles from Health and Medicine:

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

nachricht New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>