Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Secrets of potato blight evolution could help farmers fight back

31.01.2014
Scientists have discovered vital clues as to how the pathogen responsible for the Irish potato famine adapted to spread between different plant species

Scientists have discovered vital clues as to how the pathogen responsible for the Irish potato famine adapted to spread between different plant species.


Mirabilis jalapa (the four o'clock flower). This plant is the host of Phytophthora mirabilis, the sister species of the Irish potato famine pathogen Phytophthora infestans.

Credit: Sophien Kamoun, The Sainsbury Laboratory (Norwich, UK)

Researchers at Oxford University and The Sainsbury Laboratory (Norwich, UK) looked in unprecedented detail at how Phytophthora infestans, a pathogen that continues to blight potatoes and tomatoes today, evolved to target other plants.

The study, published today in the journal Science, is the first to show how pathogens switch from targeting one species to another through changes at the molecular level. Researchers examined the biochemical differences between Phytophthora infestans and sister species Phytophthora mirabilis, a pathogen that split from P. infestans around 1300 years ago to target the Mirabilis jalapa plant, commonly known as the four o'clock flower. They found that each pathogen species secretes specialized substances to shut down the defences of their target hosts.

'Plants have these enzymes called proteases that play a key role in their defence systems,' said Dr Renier van der Hoorn, co-author of the study from Oxford University's Department of Plant Sciences. 'When a plant becomes infected, proteases help plants to attack the invading pathogens and trigger immune responses. P. infestans secretes substances called effectors that disable proteases in potatoes and tomatoes. These are highly specialized to block specific proteases in the host plant, fitting like a key into a lock.'

The effectors secreted by P. infestans are less effective against proteases in other plants such as the four o'clock, as they do not fit well into the 'locks'. The researchers found that P. mirabilis evolved effectors that disable the defences of the four o'clock plant but are no longer effective against potatoes or tomatoes.

'For the first time, we have found a direct molecular mechanism underpinning the change in host specialisation,' said Dr van der Hoorn. 'We looked at specialisation in the blight pathogens' secret weapon, a key family of effectors called 'EPIC' that can pass through plants' defences undetected to disable the proteases. The EPIC effectors secreted by P. infestans have evolved to fit the structure of potato proteases just as P. mirabilis has evolved effectors that fit four o'clock proteases.

'If we could breed plants with proteases that can detect these stealthy EPIC effectors, we could prevent them from 'sneaking in' and thus make more resistant plants. Within the next decade, we plan to exploit the specialized nature of these effectors to develop proteases that are resistant to their action or can even trap them and destroy the pathogen. Potato and tomato plants with such proteases would be resistant to the blight pathogens, and combined with other resistant traits could provide another 'wall' of defence against the pathogens.'

The study was funded by the Gatsby Charitable Foundation, the UK Biotechnology and Biological Sciences Research Council, Ohio State University and the US Department of Agriculture.

News & Information Office | EurekAlert!
Further information:
http://www.ox.ac.uk

More articles from Agricultural and Forestry Science:

nachricht Plasma-zapping process could yield trans fat-free soybean oil product
02.12.2016 | Purdue University

nachricht New findings about the deformed wing virus, a major factor in honey bee colony mortality
11.11.2016 | Veterinärmedizinische Universität Wien

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Simple processing technique could cut cost of organic PV and wearable electronics

06.12.2016 | Materials Sciences

3-D printed kidney phantoms aid nuclear medicine dosing calibration

06.12.2016 | Medical Engineering

Robot on demand: Mobile machining of aircraft components with high precision

06.12.2016 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>